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Parallel Density-Based Downsampling of Cytometry Data

  • Martin Nemček
  • Tomáš JarábekEmail author
  • Mária Lucká
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 1005)

Abstract

Identification of cellular populations is the first step in analyzing cytometry data. To identify both abundant and outlying rare cellular populations a density-based preprocessing of data to equalize representations of populations is needed. Density-based downsampling keeps representative points in the cellular space while discarding irrelevant ones. We propose a fast and fully deterministic algorithm for density calculation, based on space partitioning, tree representation and an iterative approach to downsampling utilizing fast calculation of density. We compared our algorithm with SPADE, the most used approach in this area, achieving comparable results in a significantly shorter runtime.

Keywords

Downsampling Cytometry Density Parallel computing Outlier detection 

Notes

Acknowledgments

This work was partially supported by the Scientific Grant Agency of The Slovak Republic, Grant No. VG 1/0458/18 and APVV-16-0484.

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Martin Nemček
    • 1
  • Tomáš Jarábek
    • 1
    Email author
  • Mária Lucká
    • 1
  1. 1.Faculty of Informatics and Information TechnologiesSlovak University of TechnologyBratislavaSlovakia

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