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Psoriatic Arthritis and Infection

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Infections and the Rheumatic Diseases

Abstract

An infectious etiology for both psoriasis and psoriatic arthritis has long been suspected. Accumulated evidence supports a role for Gram-positive bacteria and other microorganism(s) including viral agents. Streptococci and HIV are among the leading triggering agents in combination with genetic and immune-related factors. Regarding the latter, cell-mediated and humoral-mediated mechanisms play an important role. More recently, microbiota has also been shown to participate in its pathogenesis. In this chapter, we focus on its genetics, immunology, and infectious basis. Much has been learned and much more remains.

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Vasey, F.B., Espinoza, L.R. (2019). Psoriatic Arthritis and Infection. In: Espinoza, L. (eds) Infections and the Rheumatic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-23311-2_36

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