Abstract
Rheumatic manifestations may follow a variety of viral infections. These viral infections may induce septic and reactive arthritis, and may be associated with chronic inflammatory joint diseases. New molecular techniques allow us to identify and isolate these viruses. Non-steroidal anti-inflammatory drugs or short courses of glucocorticoids have been used and reported to be of benefit. Some viruses are associated with the development of autoimmune inflammatory joint diseases, that is, systemic lupus erythematosus, Sjögren’s syndrome, and rheumatoid arthritis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ahmad N, Drew WL, Lagunoff M. Pathogenic viruses. In: Ryan Kenett J, editor. Sherris medical microbiology. 7th ed: Mc Graw-Hill Education; 2018.
Rhee EG, Johanssen EC, Crumpaker OS, Gershon AA, Witley RJ, Schiffer JT. Viruses. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases book. 8th ed: Elsevier Saunders; 2015.
Lambert N, Strebel P, Orenstein W, Icenogle J, Poland GA. Rubella. Lancet. 2015;385:2297–307.
Fry J, Dillane JB, Fry L. Rubella virus. Br Med J. 1962;2(5320):1666–7.
Loudon IS. Polyarthritis in rubella. Br Med J. 1953;1:1388.
Kantor T, Tannes M. Rubella arthritis and rheumatoid arthritis. Arthritis Rheum. 1962;5:378–83.
Lee PR, Barnett AF, Scholer JF. Rubella arthritis—a study of twenty cases. Calif Med. 1960;93:125–8.
Chambers RJ, Bywaters EGL. Rubella synovitis. Ann Rheum Dis. 1963;22:263–8.
Yanez JE, Thompson GR, Mikkelsen WM, Bartholomew LE. Rubella arthritis. Ann Intern Med. 1966;64:772–7.
Smith D, Guzowska J. Arthritis complicating rubella. Med J Aust. 1970;1:845–7.
Miller WH, Curl OJ. Arthritis complicating rubella in a recent epidemic. Practitioner. 1963;190:515–7.
Johnston INL. Complications of rubella. BMJ. 1962;2:414.
Hildebrandt HM, Maassab HB. Rubella synovitis in a one-year-old patient. N Engl J Med. 1966;274:1428–30.
Best JM. Rubella vaccines: past, present and future. Epidemiol Infect. 1991;107:17–30.
Cooper LZ, Ziring PR, Weiss HJ, et al. Transient arthritis after rubella vaccination. Am J Dis Child. 1969;118:218–25.
Horstmann DM, Liebhaber H, Kohorn EI. Post-partum vaccination of rubella-susceptible women. Lancet. 1970;2:1003–6.
Barnes EK, Altman R, Austin SM, Dougherty WJ. Joint reactions in children vaccinated against rubella. Study II: comparison of the three vaccines. Am J Epidemiol. 1972;95:59–66.
Dudgeon AJ, Marshall W, Peckham C. Rubella vaccinated trials in adults and children. Am J Dis Child. 1969;118:237–42.
Spruance SL, Smith CB. Joint complications associated with derivatives of HPV-77rubella virus vaccine. Am J Dis Child. 1971;122:105–11.
Thompson G, Ferreyra A, Brackett RG. Acute arthritis complicating rubella vaccination. Arthritis Rheum. 1971;14:19–26.
Swartz TA, Klingberg W, Goldwasser RA. Clinical manifestations, according to age, among females given HPV-77 duck embryo vaccine. Am J Epidemiol. 1971;94:246–51.
Polk BF, Modlin JF, White JA, DeGirolami PC. A controlled comparison of joint reactions among women receiving one of two rubella vaccines. Am J Epidemiol. 1982;115:19–25.
Tingle AJ, Yang T, Allen M, Kettyls GD, Larke RP, Schulzer M. Prospective immunological assessment of arthritis induced by rubella vaccine. Infect Immun. 1983;40:22–8.
Tingle AJ, Allen M, Petty RE, Kettyls GD, Chantler JK. l Rubella-associated arthritis. I. Comparative study of joint manifestations associated with natural rubella infection and RA 27/3 rubella immunization. Ann Rheum Dis. 1986;45:110–4.
Singh VK, Tingle AJ, Schulzer M. Rubella-associated arthritis. II. Relationship between circulating immune complex levels and joint manifestations. Ann Rheum Dis. 1986;45:115–9.
Wallace RB, Liber P, Ibrahim M, lsacson P. Joint symptoms following an area-wide rubella immunization campaign--report of a survey. Am J Public Health. 1972;62:658–61.
Weibel RE, Stokes J, Buynak EB, et al. Live rubella vaccines in adults and children. Am J Dis Child. 1969;118:226–9.
Weibel RE, Stokes J, Buynak EB, et al. Influence of age on clinical response to HPV-77 rubella vaccine duck. JAMA. 1972;222:805–7.
Lerman SJ, Nankervis GA, Heggie AD. Immunologic response, virus exception, and joint reaction with Rubella vaccine. Ann Intern Med. 1971;74:67–73.
Thompson GR, Weiss JJ, Shilis JL. Intermittent arthritis following rubella vaccination. Am J Dis Child. 1973;125:526–30.
Ogra PL, Herd KJ. Arthritis associated with induced rubella infection. J Immunol. 1971;107:810–3.
Weibel RE, Stokes J, Buynak EB. Rubella vaccination in adults females. N Engl J Med. 1969;280:682–5.
Spruance SL, Metcalf R, Smith CB, et al. Chronic arthropathy associated with rubella vaccination. Arthritis Rheum. 1977;20:741–7.
Spruance SL, Klock LE, Bailey A, et al. Recurrent joint symptom in children vaccinated with HPV-77DK 12 rubella vaccine. J Pediatr. 1972;80:413–7.
Grahame R, Armstrong R, Simmons N, Wilton JM, Dyson M, Laurent R, Millis R, Mims CA. Chronic arthritis associated with the presence of intrasynovial rubella virus. Ann Rheum Dis. 1983;42:2–13.
Chantler JK, Tingle AJ, Petty RE. Persistent rubella virus infection associated with chronic arthritis in children. N Engl J Med. 1985;313:1117–23.
Bosma TJ, Etherington J, O’Shea S, Corbett K, Cottam F, Holt L, Banatvala JE, Best JM. Rubella virus and chronic joint disease: is there an association? J Clin Microbiol. 1998;36:3524–6.
Lynch JP 3rd, Kajon AE. Adenovirus: epidemiology, global spread of novel serotypes, and advances in treatment and prevention. Semin Respir Crit Care Med. 2016;37:586–602.
Lion T. Adenovirus infections in immunocompetent and immunocompromised patients. Clin Microbiol Rev. 2014;27:441–62.
Scott MK, Chommanard C, Lu X, et al. Human adenovirus associated with severe respiratory infection, Oregon, USA, 2013–2014. Emerg Infect Dis. 2016;22:1044–51.
Centers for Disease Control. Acute respiratory disease associated with adenovirus serotype 14—four states, 2006-2007. MMWR Morb Mortal Wkly Rep. 2007;56:1181–4.
Lamson DM, Kajon A, Shudt M, Girouard G, St George K. Detection and genetic characterization of adenovirus type 14 strain in students with influenza-like illness, New York, USA, 2014–2015. Emerg Infect Dis. 2017;23:1194.
Panush RS. Adenovirus arthritis. Arthritis Rheum. 1974;17:534–6.
Utsinger PD. Immunologic study of arthritis associated with adenovirus infection. Arthritis Rheum. 1977;20:138.
Meyer-Bahlburg A, Dressler F, Baumann U. Chronic arthritis in a boy with Cernunnos immunodeficiency. Clin Immunol. 2014;154:47–8.
Shetty AK, Treynor E, Hill DW, Gutierrez KM, Warford A, Baron EJ. Comparison of conventional viral cultures with direct fluorescent antibody stains for diagnosis of community-acquired respiratory virus infections in hospitalized children. Pediatr Infect Dis J. 2003;22:789–94.
Terletskaia-Ladwig E, Leinmuller M, Schneider F, Meier S, Enders M. Laboratory approaches to the diagnosis of adenovirus infection depending on clinical manifestations. Infection. 2007;35:438–43.
Kidd A, Jonsson M, Garwicz D, et al. Rapid subgenus identification of human adenovirus isolates by a general PCR. J Clin Microbiol. 1996;34:622–7.
Xu W, Mcdonough MC, Erdman DD. Species-specific identification of human adenoviruses by a multiplex PCR assay. J Clin Microbiol. 2000;38:4114–20.
Buckwalter SP, Teo R, Espy MJ, Sloan LM, Smith TF, Pritt BS. Real-time qualitative PCR for 57 human adenovirus types from multiple specimen sources. J Clin Microbio. 2012;50:766–71.
Ganzenmueller T, Heim A. Adenoviral load diagnostics by quantitative polymerase chain reaction: techniques and application. Rev Med Virol. 2012;22:194–208.
Jeulin H, Salmon A, Bordigoni P, Venard V. Comparison of in-house real time quantitative PCR to the Adenovirus R-Gene kit for determination of adenovirus load in clinical samples. J Clin Microbiol. 2010;48:3132–7.
De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: problems and solutions. World J Virol. 2012;1:31–43.
Bernstein A. Infectious mononucleosis. Medicine. 1940;19:85–159.
Chervenick PA. Infectious mononucleosis. Dis Mon. 1974:1–29.
Adebonojo FO. Monoarticular arthritis: an unusual manifestation of infectious mononucleosis. Clin Pediatr (Phila). 1972;11:549–50.
Berger RG, Raab-Traub N. Acute monoarthritis from infectious mononucleosis. Am J Med. 1999;107:177–8.
Pollack S, Enat R, Barzilai D. Monoarthritis with heterophil-negative infectious mononucleosis. Case of an older patient. Arch Intern Med. 1980;140:1109–11.
Gómez N, Rey R, Ibáñez J. Acute oligoarthritis and infection by Epstein-Barr virus. Enferm Infecc Microbiol Clin. 1998;16:440–1.
Feced CM, Fernández M, Robustillo M, De la Morena I, Alegre JJ. Joint involvement secondary to Epstein-Barr virus. Reumatol Clin. 2016;12:100–2.
Urman JD, Bobrove AM. Acute polyarthritis and infectious mononucleosis. West J Med. 1982;136:151–3.
Sigal LH, Steere AC, Niederman JC. Symmetric polyarthritis associated with heterophile-negative infectious mononucleosis. Arthritis Rheum. 1983;26:553–6.
Evans ASEB. Virus antibody in systemic lupus erythematosus. Lancet. 1971;1:1023–4.
Toussirot E, Roudier J. Epstein-Barr virus in autoimmune diseases. Best Pract Res Clin Rheumatol. 2008;22:883–96.
Esposito S, Bosis S, Semino M, et al. Infections and systemic lupus erythematosus. Eur J Clin Microbiol Infect Dis. 2014;33:1467–75.
Fattal I, Shental N, Molad Y, et al. Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA. Immunology. 2014;141:276–85.
Rasmussen NS, Draborg AH, Nielsen CT, et al. Antibodies to early EBV, CMV, and HHV6 antigens in systemic lupus erythematosus patients. Scand J Rheumatol. 2015;44:143–9.
Ball RJ, Avenell A, Aucott L, Hanlon P, Vickers MA. Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and systemic lupus erythematosus. Arthritis Res Ther. 2014;16:R3.
Croia C, Astorri E, Murray-Brown W, et al. Implication of Epstein-Barr virus infection in disease-specific autoreactive B-cell activation in ectopic lymphoid structures of Sjogren’s syndrome. Arthritis Rheumatol. 2014;66:2545–57.
Kivity S, Arango MT, Ehrenfeld M, et al. Infection and autoimmunity in Sjogren’s syndrome: a clinical study and comprehensive review. J Autoimmun. 2014;51:17–22.
Erre GL, Mameli G, Cossu D, et al. Increased Epstein-Barr virus DNA load and antibodies against EBNA1 and EA in sardinian patients with rheumatoid arthritis. Viral Immunol. 2015;28:385–90.
Ball RJ, Avenell A, Aucott L, Hanlon P, Vickers MA. Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and rheumatoid arthritis. Arthritis Res Ther. 2015;17:274.
Harley JB, Chen X, Pujato M, Miller D, Maddox A, Forney C, et al. Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. Nat Genet. 2018;50:699–70.
Ward JR, Bishop B. Varicella arthritis. JAMA. 1970;212:1954–6.
Fink CG, Read SJ, Giddins G, Eglin RP. Chicken pox infection (varicella zoster virus) and acute monoarthritis: evidence against a direct viral mechanism. J Clin Pathol. 1992;45:267–9.
Brook I. Varicella arthritis in childhood. Reports of 2 cases and 4 others found in the literature. Clin Pediatr (Phila). 1977;16:1156–7.
Gibson NF, Ogden WS. Varicella arthritis. South Med J. 1986;79:1028–30.
Bevilacqua S, Poircuitte JM, Boyer L, May T, Lascombes P, Venard V. Varicella Arthritis in Childhood: a case report and review of the literature. Pediatr Infect Dis J. 2011;30:980–2.
Fierman AH. Varicella-associated arthritis occurring before the exanthem. Case report and literature review. Clin Pediatr (Phila). 1990;29:188–90.
Stebbings S, Highton J, Croxson MC, Powell K, McKay J, Rietveld J. Chickenpox monoarthritis: demonstration of varicella-zoster virus in joint fluid by polymerase chain reaction. Br J Rheumatol. 1998;37:311–3.
Chen MK, Wang CC, Lu JJ, Perng CL, Chu ML. Varicella arthritis diagnosed by polymerase chain reaction. J Formos Med Assoc. 1999;98:519–21.
Evans E, Dawes PT, Mattey DL. An unusual case of adult varicella-associated arthritis. Rheumatology (Oxford). 2000;39:806–8.
Caranasos GJ, Felker JR. Mumps arthritis. Arch Intern Med. 1967;119:394–8.
Solem JH. Mumps arthritis without parotitis. Scand J Infect Dis. 1971;3:173–5.
Maris EP, Enders JF, Stokes J, Kane LW. Immunity in Mumps: IV. The Correlation of the Presence of Complement-fixing antibody and resistance to Mumps in Human Beings. J Exp Med. 1946;84:323–39.
Gordon SC, Lauter CB. Mumps arthritis. A review of the literature. Rev Infect Dis. 1984;6:338–44.
Nikonov OS, Chernykh ES, Garber MB, Nikonova EY. Enteroviruses: classification, diseases they cause, and approaches to development of antiviral drugs. Biochemistry (Mosc). 2017;82:1615–31.
Sanford JP, Sulkin SE. The clinical spectrum of ECHO-virus infection. N Engl J Med. 1959;261:1113–22.
Hurst NP, Martynoga AG, Nuki G, Sewell JR, Mitchell A, Hughes GR. Coxsackie B infection and arthritis. Br Med J (Clin Res Ed). 1983;286:605.
Rahal JJ, Millian SJ, Noriega ER. Coxsackievirus and adenovirus infection. Association with acute febrile and juvenile rheumatoid arthritis. JAMA. 1976;7(235):2496–501.
Blotzer JW, Myers AR. Echovirus-associated polyarthritis. Report of a case with synovial fluid and synovial histologic characterization. Arthritis Rheum. 1978;21:978–81.
Kujala G, Newman JH. Isolation of echovirus type 11 from synovial fluid in acute monocytic arthritis. Arthritis Rheum. 1985;28:98–9.
Triantafyllopoulou A, Tapinos N, Moutsopoulos HM. Evidence for coxsackievirus infection in primary sjogren’s syndrome. Arthritis Rheum. 2004;50:2897–902.
Gandhi MK, Khanna R. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect Dis. 2004;4:725–38.
Friedman HM, Pincus T, Gibilisco P, Baker D, et al. Acute monoarticular arthritis caused by herpes simplex virus and cytomegalovirus. Am J Med. 1980;69:241–7.
Halenius A, Hengel H. Human cytomegalovirus and autoimmune disease. Biomed Res Int. 2014;2014:1–15.
Dolcino M, Puccetti A, Barbieri A, Bason C, Tinazzi E, Ottria A, et al. Infections and autoimmunity: role of human cytomegalovirus in autoimmune endothelial cell damage. Lupus. 2015;24:419–32.
Brna JA, Hall RF Jr. Acute monoarticular herpetic arthritis. J Bone Joint Surg. 1984;66-A:623.
Shelley WB. Herpetic arthritis associated with disseminate herpes simplex in a wrestler. Br J Dermatol. 1980;103:209–12.
Naraqi S, Jackson GG, Jonasson OM. Viremia with herpes simplex type 1 in adults: four nonfatal cases, one with features of chicken pox. Ann Int Med. 1976;85:165–9.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Vega, L.E., Espinoza, L.R. (2019). Other Viral Arthritides. In: Espinoza, L. (eds) Infections and the Rheumatic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-23311-2_17
Download citation
DOI: https://doi.org/10.1007/978-3-030-23311-2_17
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-23310-5
Online ISBN: 978-3-030-23311-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)