Abstract
Chromatin modifying enzymes either add or remove post-translational modifications to histone proteins and in this way change the functional profile of the epigenome. Antagonizing enzymes, such as HATs and HDACs, often co-localize at chromatin regions and fine-tune gene expression. Chromatin modeling complexes change the structure of chromatin by shifting, evicting or replacing nucleosomes. Finally, also long ncRNAs, such as Xist, can affect chromatin structure and function.
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Carlberg, C., Molnár, F. (2019). Chromatin Modifying Proteins and RNAs. In: Human Epigenetics: How Science Works. Springer, Cham. https://doi.org/10.1007/978-3-030-22907-8_5
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DOI: https://doi.org/10.1007/978-3-030-22907-8_5
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