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Pediatric Rhinosinusitis pp 95–106Cite as

Rhinosinusitis and Asthma in Children

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Abstract

The upper and lower respiratory tracts may be considered as a single morphological and functional unit. Physiologically, the role of the upper airway includes the protection of the lower airway by conditioning the inhaled air through filtration, humidification, and warming. There is growing evidence that inflammatory diseases of the airway, such as allergic rhinitis, chronic rhinosinusitis (CRS), and bronchial asthma, are manifestations of the same or similar pathological processes but in different parts of the respiratory tract. These diseases frequently have the same triggers: aeroallergens, aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), irritants, and viral and bacterial infections. The concept of a “unified airway” has been proposed as an integrated term to cover the relationship between the upper and lower airways as well as their mutual effects on each other.

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Disclosure Statement

All authors have no direct financial interest in subject matter or materials discussed in article or with a company making a competing product. Dr. Phipatanakul would like to acknowledge NIH funding K24 AI 106822 for research into the content described in this chapter.

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Authors and Affiliations

  1. Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon

    Ahmad Salaheddine Naja

  2. Department of Otolaryngology–Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA

    Ahmad R. Sedaghat

  3. Division of Allergy and Immunology, Boston Children’s Hospital, Boston, MA, USA

    Wanda Phipatanakul

  4. Department of Pediatrics, Harvard Medical School, Boston, MA, USA

    Wanda Phipatanakul

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  1. Ahmad Salaheddine Naja
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  2. Ahmad R. Sedaghat
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  3. Wanda Phipatanakul
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Correspondence to Wanda Phipatanakul .

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Editors and Affiliations

  1. Department of Otolaryngology, West Virginia University, School of Medicine, Morgantown, WV, USA

    Hassan H. Ramadan

  2. Section of Otolaryngology–Head and Neck Surgery, The University of Chicago Medicine and The Comer Children’s Hospital, Chicago, IL, USA

    Fuad M. Baroody

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Naja, A.S., Sedaghat, A.R., Phipatanakul, W. (2020). Rhinosinusitis and Asthma in Children. In: Ramadan, H., Baroody, F. (eds) Pediatric Rhinosinusitis. Springer, Cham. https://doi.org/10.1007/978-3-030-22891-0_8

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  • DOI: https://doi.org/10.1007/978-3-030-22891-0_8

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