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Scalp Itch Treatment

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Hair and Scalp Treatments

Abstract

Scalp itch is a common cause of complaint in the dermatological setting and also accompanies many of the scalp disorders. When possible, the first step to treat scalp pruritus is to find the underlying cause. A thorough evaluation must comprehend a complete interrogatory, clinical, and trichoscopical evaluation and sample taking when necessary.

Management of scalp itching includes hygiene recommendations and topical and systemic antipruritic treatment. Itch perception and its impact on quality of life must be taken into account when deciding the treatment of choice.

Specific scalp conditions respond to treatment according to their mechanism for causing itch.

In order to help attenuate scalp itch, helping skin barrier and microflora balance, general antipruritic management, specific itch-mediator targeting, and subjacent disease treatment must be combined.

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References

  1. Vázquez-Herrera NE, Sharma D, Aleid NM, Tosti A. Scalp itch: a systematic review. Skin Appendage Disord. 2018;4(3):187–99.

    Article  PubMed  Google Scholar 

  2. Schut C, Mollanazar N, Kupfer J, Gieler U, Yosipovitch G. Psychological interventions in the treatment of chronic itch. Acta Derm Venereol. 2016;96(2):157–61.

    Article  PubMed  Google Scholar 

  3. Rácz E, Gho C, Moorman PW, Noordhoek Hegt V, Neumann HAM. Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review. J Eur Acad Dermatol Venereol. 2013;27(12):1461–70.

    Article  PubMed  Google Scholar 

  4. Munro DD. Topical corticosteroid therapy and its effect on the hypothalamic-pituitary-adrenal axis. Dermatology. 1976;152(1):173–80.

    Article  CAS  Google Scholar 

  5. Pereira U, Boulais N, Lebonvallet N, Pennec JP, Dorange G, Misery L. Mechanisms of the sensory effects of tacrolimus on the skin. Br J Dermatol. 2010;163(1):70–7.

    CAS  PubMed  Google Scholar 

  6. Kaufmann R, Bieber T, Helgesen AL, Andersen BL, Luger T, Poulin Y, et al. Onset of pruritus relief with pimecrolimus cream 1% in adult patients with atopic dermatitis: a randomized trial. Allergy. 2006;61(3):375–81.

    Article  CAS  PubMed  Google Scholar 

  7. Bernstein JE, Whitney DH, Soltani K. Inhibition of histamine-induced pruritus by topical tricyclic antidepressants. J Am Acad Dermatol. 1981;5(5):582–5.

    Article  CAS  PubMed  Google Scholar 

  8. Yosipovitch G, Gold L, Lebwohl M, Silverberg J, Tallman A, Zane L. Early relief of pruritus in atopic dermatitis with crisaborole ointment, a non-steroidal, phosphodiesterase 4 inhibitor. Acta Derm Venereol. 2018;98(5):484–9.

    Article  PubMed  Google Scholar 

  9. Prignano F, Ricceri F, Pescitelli L, Lotti T. Itch in psoriasis: epidemiology, clinical aspects and treatment options. Clin Cosmet Investig Dermatol. 2009;2:9–13.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Draelos ZD. An evaluation of topical 3% salicylic acid and 1% hydrocortisone in the maintenance of scalp pruritus. J Cosmet Dermatol. 2005;4(3):193–7.

    Article  PubMed  Google Scholar 

  11. Papoiu A, Valdes-Rodriguez R, Nattkemper L, Chan Y, Hahn G, Yosipovitch G. A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch. Acta Derm Venereol. 2013;93(5):520–6.

    Article  PubMed  Google Scholar 

  12. Elmariah SB, Lerner EA. Topical therapies for pruritus. Semin Cutan Med Surg. 2011;30(2):118–26.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Tey HL, Yosipovitch G. Targeted treatment of pruritus: a look into the future. Br J Dermatol. 2011;165(1):5–17.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Visse K, Blome C, Phan N, Augustin M, Ständer S. Efficacy of body lotion containing N-palmitoylethanolamine in subjects with chronic pruritus due to dry skin: a dermatocosmetic study. Acta Derm Venereol. 2017;97(5):639–41.

    Article  PubMed  Google Scholar 

  15. Şavk E. Neurologic itch management. Curr Probl Dermatol. 2016;50:116–23.

    Article  PubMed  Google Scholar 

  16. Stull C, Grossman S, Yosipovitch G. Current and emerging therapies for itch management in psoriasis. Am J Clin Dermatol. 2016;17(6):617–24.

    Article  PubMed  Google Scholar 

  17. Hussain Z, Thu HE, Shuid AN, Kesharwani P, Khan S, Hussain F. Phytotherapeutic potential of natural herbal medicines for the treatment of mild-to-severe atopic dermatitis: a review of human clinical studies. Biomed Pharmacother. 2017;93:596–608.

    Article  PubMed  Google Scholar 

  18. Schweiger D, Baufeld C, Drescher P, Oltrogge B, Höpfner S, Mess A, et al. Efficacy of a new tonic containing urea, lactate, polidocanol, and glycyrrhiza inflata root extract in the treatment of a dry, itchy, and subclinically inflamed scalp. Skin Pharmacol Physiol. 2013;26(2):108–18.

    Article  CAS  PubMed  Google Scholar 

  19. Feramisco JD, Berger TG, Steinhoff M. Innovative management of pruritus. Dermatol Clin. 2010;28(3):467–78.

    Article  CAS  PubMed  Google Scholar 

  20. Rosner MH. Cromolyn sodium: a potential therapy for uremic pruritus? Hemodial Int. 2006;10(2):189–92.

    Article  PubMed  Google Scholar 

  21. Rishnan A, Koo J. Psyche, opioids, and itch. Dermatol Ther. 2005;18(4):314–22.

    Article  Google Scholar 

  22. Tarikci N, Kocatürk E, Güngör F, Topal IGOL, Can PÜ, Singer R. Pruritus in systemic diseases: a review of etiological factors and new treatment modalities. ScientificWorldJournal. 2015;2015:803752.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Neff GW, O’brien CB, Reddy KR, Bergasa NV, Regev A, Molina E, et al. Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. Am J Gastroenterol. 2002;97(8):2117–9.

    Article  PubMed  Google Scholar 

  24. Bin Saif G, Ericson ME, Yosipovitch G. The itchy scalp--scratching for an explanation. Exp Dermatol. 2011;20(12):959–68.

    Article  CAS  PubMed  Google Scholar 

  25. Yosipovitch G, Samuel LS. Neuropathic and psychogenic itch. Dermatol Ther. 2008;21(1):32–41.

    Article  PubMed  Google Scholar 

  26. Misery L, Alexandre S, Dutray S, Chastaing M, Consoli SG, Audra H, et al. Functional itch disorder or psychogenic pruritus: suggested diagnosis criteria from the French Psychodermatology Group. Acta Derm Venereol. 2007;87(4):341–4.

    Article  PubMed  Google Scholar 

  27. Szepietowski JC, Reszke R. Psychogenic itch management. Curr Probl Dermatol. 2016;50:124–32.

    Article  PubMed  Google Scholar 

  28. Shaw RJ, Dayal S, Good J, Bruckner AL, Joshi SV. Psychiatric medications for the treatment of pruritus. Psychosom Med. 2007;69(9):970–8.

    Article  PubMed  Google Scholar 

  29. Rowe B, Yosipovitch G. Paraneoplastic itch management. Curr Probl Dermatol. 2016;50:149–54.

    Article  PubMed  Google Scholar 

  30. Ishikawa C, Tsuda T, Konishi H, Nakagawa N, Yamanishi K. Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. Antimicrob Agents Chemother. 2009;53(5):1760–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. He A, Alhariri JM, Sweren RJ, Kwatra MM, Kwatra SG. Aprepitant for the treatment of chronic refractory pruritus. Biomed Res Int. 2017;2017:4790810.

    PubMed  PubMed Central  Google Scholar 

  32. Zeidler C, Yosipovitch G, Ständer S. Prurigo nodularis and its management. Dermatol Clin. 2018;36(3):189–97.

    Article  CAS  PubMed  Google Scholar 

  33. Ding D-F, Li R-C, Xiong Q-J, Zhou L, Xiang H-B. Pulsed radiofrequency to the great occipital nerve for the treatment of intractable postherpetic itch: a case report. Int J Clin Exp Med. 2014;7(10):3497–500.

    PubMed  PubMed Central  Google Scholar 

  34. Schröder L, Hertl M, Chatzigeorgakidis E, Phan NQ, Ständer S. Chronic pruritus in autoimmune dermatoses. Hautarzt. 2012;63(7):558–66.

    Article  PubMed  Google Scholar 

  35. Haber JS, Valdes-Rodriguez R, Yosipovitch G. Chronic pruritus and connective tissue disorders: review, gaps, and future directions. Am J Clin Dermatol. 2016;17(5):445–9.

    Article  PubMed  Google Scholar 

  36. Welz-Kubiak K, Reich A. Mediators of pruritus in lichen planus. Autoimmune Dis. 2013;2013:941431.

    PubMed  PubMed Central  Google Scholar 

  37. Cohen AD, Andrews ID, Medvedovsky E, Peleg R, Vardy DA. Similarities between neuropathic pruritus sites and lichen simplex chronicus sites. Isr Med Assoc J. 2014;16(2):88–90.

    PubMed  Google Scholar 

  38. Yosipovitch G. Chronic pruritus: a paraneoplastic sign. Dermatol Ther. 2010;23(6):590–6.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Serrano L, Martinez-Escala ME, Zhou XA, Guitart J. Pruritus in cutaneous T-cell lymphoma and its management. Dermatol Clin. 2018;36(3):245–58.

    Article  CAS  PubMed  Google Scholar 

  40. Yosipovitch G, Mills KC, Nattkemper LA, Feneran A, Tey HL, Lowenthal BM, et al. Association of pain and Itch with depth of invasion and inflammatory cell constitution in skin cancer. JAMA Dermatol. 2014;150(11):1160.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Antonella Tosti .

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Vazquez-Herrera, N.E., Tosti, A. (2020). Scalp Itch Treatment. In: Tosti, A., Asz-Sigall, D., Pirmez, R. (eds) Hair and Scalp Treatments. Springer, Cham. https://doi.org/10.1007/978-3-030-21555-2_15

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  • DOI: https://doi.org/10.1007/978-3-030-21555-2_15

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-21555-2

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