Abstract
Due to several reasons, animals are preferred for producing recombinant therapeutics . At present, it is possible to synthesize genes , or extract genes of interest, and introduce them into across cell membranes by means of viral vectors , electroporation or mechanically. The newly introduced enzymatic methods of gene modifications are easy, precise , and cheaper and used in human gene therapies , biomedical sciences, and livestock genome manipulation . Gene-edited livestock is poised to become a commercial reality for producing transgenic or model animals.
Highlights
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Repertoire of molecular tools allow precise modification of genome at rapid pace and precision
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Instead of yeasts and animals cells, the animals are preferred for producing recombinant therapeutic proteins
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Significant improvements are made in modifying genomes by enzyme -catalyzed methods of gene manipulation.
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Singh, B., Mal, G., Gautam, S.K., Mukesh, M. (2019). Genome Editing in Farm Animals. In: Advances in Animal Biotechnology. Springer, Cham. https://doi.org/10.1007/978-3-030-21309-1_42
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