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Widespread Erythema and Skin Desquamation

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Pediatric Immunology

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Abstract

Omenn syndrome should be suspected at an early age upon recognition of characteristic phenotypic manifestations: erythroderma, desquamation of the skin, enlargement of the lymph nodes, diarrhea, eosinophilia, and hyper-IgE

In our case autoimmunity manifested before recurrent infections developed, complicating the diagnosis, hence improvement was achieved by using immunosuppressive agents

Non-X-ray treated plasma transfusion deteriorated the patient’s condition, as well as the prognosis of future hematopoietic stem-cell transplant, due to GVHD-like reaction as a result of donor T lymphocytes

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Authors and Affiliations

  1. Shupyk National Medical Academy for Postgraduate Education, Department of Pediatric Infectious Diseases and Pediatric Immunology, Kiev, Ukraine

    Anastasiia Bondarenko & Liudmyla Chernyshova

Authors
  1. Anastasiia Bondarenko
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  2. Liudmyla Chernyshova
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Editor information

Editors and Affiliations

  1. Department of Immunology, School of Medicine, Research Center for Immunodeficiencies (RCID)Children’s Medical Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran

    Nima Rezaei

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Bondarenko, A., Chernyshova, L. (2019). Widespread Erythema and Skin Desquamation. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_33

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  • DOI: https://doi.org/10.1007/978-3-030-21262-9_33

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21261-2

  • Online ISBN: 978-3-030-21262-9

  • eBook Packages: MedicineMedicine (R0)

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