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Pediatric Immunology pp 133–138Cite as

Respiratory Distress and Hypoxemia

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Abstract

Severe Combined Immunodeficiency (SCID) is a paediatric emergency as it can be rapidly fatal

Clinical suspicion is essential as clinical presentation may be nonspecific

Immunophenotyping is extremely important for the diagnosis but it must be confirmed by molecular characterization

Early diagnosis and hematopoietic stem cells transplantation improves the survival of SCID patients

Supportive care and management of infections from the time of diagnosis until transplantation are of utmost importance

SCID neonatal screening is a promising option for earlier diagnosis and treatment.

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Author information

Authors and Affiliations

  1. Paediatric Infectious Diseases and Immunodeficiencies Unit, Centro Materno-Infantil do Norte, Centro Hospitalar do Porto, Porto, Portugal

    Laura Marques

  2. Immunology Department, Centro Hospitalar do Porto, Porto, Portugal

    Lidia Branco, Julia Vasconcelos & Esmeralda Neves

  3. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Porto, Portugal

    Esmeralda Neves

Authors
  1. Laura Marques
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  2. Lidia Branco
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  3. Julia Vasconcelos
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  4. Esmeralda Neves
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Editor information

Editors and Affiliations

  1. Department of Immunology, School of Medicine, Research Center for Immunodeficiencies (RCID)Children’s Medical Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran

    Nima Rezaei

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Marques, L., Branco, L., Vasconcelos, J., Neves, E. (2019). Respiratory Distress and Hypoxemia. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_27

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  • DOI: https://doi.org/10.1007/978-3-030-21262-9_27

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21261-2

  • Online ISBN: 978-3-030-21262-9

  • eBook Packages: MedicineMedicine (R0)

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