Abstract
In this chapter, we discuss the function and mechanism of action of secreted or delivered bacterial protein toxins and effectors. The multitude of their effects on host cell physiology, architecture, signaling, and survival is framed in the context of the advantage their activity has on the success of the bacterium during infection. Concepts that lead the learner to consider how targeted intervention disables the disease-causing ability of the pathogenic bacteria are stressed, as is how the bacterium regulates such proteins to be maximally effective. The learner will be well versed in the basic biology of bacterial protein toxin/effector concepts and the important role these microbial agents of warfare play in the subversion of their eukaryotic hosts.
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Maresso, A.W. (2019). Bacterial Protein Toxins and Effectors. In: Bacterial Virulence. Springer, Cham. https://doi.org/10.1007/978-3-030-20464-8_10
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DOI: https://doi.org/10.1007/978-3-030-20464-8_10
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