Skip to main content

Multifold Acceleration of Diffusion MRI via Deep Learning Reconstruction from Slice-Undersampled Data

  • Conference paper
  • First Online:
Information Processing in Medical Imaging (IPMI 2019)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11492))

Included in the following conference series:

Abstract

Diffusion MRI (dMRI), while powerful for characterization of tissue microstructure, suffers from long acquisition time. In this paper, we present a method for effective diffusion MRI reconstruction from slice-undersampled data. Instead of full diffusion-weighted (DW) image volumes, only a subsample of equally-spaced slices need to be acquired. We show that complementary information from DW volumes corresponding to different diffusion wavevectors can be harnessed using graph convolutional neural networks for reconstruction of the full DW volumes. The experimental results indicate a high acceleration factor of up to 5 can be achieved with minimal information loss.

This work was supported in part by NIH grants (NS093842, EB022880, and EB006733).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Albay, E., Demir, U., Unal, G.: Diffusion MRI spatial super-resolution using generative adversarial networks. In: Rekik, I., Unal, G., Adeli, E., Park, S.H. (eds.) PRIME 2018. LNCS, vol. 11121, pp. 155–163. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00320-3_19

    Chapter  Google Scholar 

  2. Bronstein, M.M., Bruna, J., LeCun, Y., Szlam, A., Vandergheynst, P.: Geometric deep learning: going beyond Euclidean data. IEEE Sig. Process. Mag. 34(4), 18–42 (2017)

    Article  Google Scholar 

  3. Bruna, J., Zaremba, W., Szlam, A., LeCun, Y.: Spectral networks and locally connected networks on graphs. arXiv preprint arXiv:1312.6203 (2013)

  4. Chen, G., Dong, B., Zhang, Y., Shen, D., Yap, P.-T.: Neighborhood matching for curved domains with application to denoising in diffusion MRI. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10433, pp. 629–637. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66182-7_72

    Chapter  Google Scholar 

  5. Defferrard, M., Bresson, X., Vandergheynst, P.: Convolutional neural networks on graphs with fast localized spectral filtering. In: Advances in Neural Information Processing Systems (NIPS), pp. 3844–3852 (2016)

    Google Scholar 

  6. Dhillon, I.S., Guan, Y., Kulis, B.: Weighted graph cuts without eigenvectors a multilevel approach. IEEE Trans. Pattern Anal. Mach. Intell. 29(11), 1944–1957 (2007)

    Article  Google Scholar 

  7. Goodfellow, I., et al.: Generative adversarial nets. In: Advances in Neural Information Processing Systems (NIPS), pp. 2672–2680 (2014)

    Google Scholar 

  8. Greenspan, H., Oz, G., Kiryati, N., Peled, S.: MRI inter-slice reconstruction using super-resolution. Magn. Reson. Imaging 20(5), 437–446 (2002)

    Article  Google Scholar 

  9. Hammond, D.K., Vandergheynst, P., Gribonval, R.: Wavelets on graphs via spectral graph theory. Appl. Comput. Harmon. Anal. 30(2), 129–150 (2011)

    Article  MathSciNet  Google Scholar 

  10. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Computer vision and pattern recognition (CVPR), pp. 770–778 (2016)

    Google Scholar 

  11. Henaff, M., Bruna, J., LeCun, Y.: Deep convolutional networks on graph-structured data. arXiv preprint arXiv:1506.05163 (2015)

  12. Isola, P., Zhu, J.Y., Zhou, T., Efros, A.A.: Image-to-image translation with conditional adversarial networks. In: Computer Vision and Pattern Recognition (CVPR), pp. 1125–1134 (2017)

    Google Scholar 

  13. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Computer Vision and Pattern Recognition (CVPR), pp. 3431–3440 (2015)

    Google Scholar 

  14. Mori, S., Crain, B.J., Chacko, V.P., Van Zijl, P.C.: Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann. Neurol. 45(2), 265–269 (1999)

    Article  Google Scholar 

  15. Nie, D., Wang, L., Adeli, E., Lao, C., Lin, W., Shen, D.: 3-D fully convolutional networks for multimodal isointense infant brain image segmentation. IEEE Trans. Cybern. 49(3), 1123–1136 (2019)

    Article  Google Scholar 

  16. Ning, L., et al.: Sparse reconstruction challenge for diffusion MRI: validation on a physical phantom to determine which acquisition scheme and analysis method to use? Med. Image Anal. 26(1), 316–331 (2015)

    Article  Google Scholar 

  17. Ning, L., et al.: A joint compressed-sensing and super-resolution approach for very high-resolution diffusion imaging. NeuroImage 125, 386–400 (2016)

    Article  Google Scholar 

  18. Peled, S., Yeshurun, Y.: Superresolution in MRI: application to human white matter fiber tract visualization by diffusion tensor imaging. Magn. Reson. Med. 45(1), 29–35 (2001)

    Article  Google Scholar 

  19. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  20. Scherrer, B., Afacan, O., Taquet, M., Prabhu, S.P., Gholipour, A., Warfield, S.K.: Accelerated high spatial resolution diffusion-weighted imaging. In: Ourselin, S., Alexander, D.C., Westin, C.-F., Cardoso, M.J. (eds.) IPMI 2015. LNCS, vol. 9123, pp. 69–81. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-19992-4_6

    Chapter  Google Scholar 

  21. Scherrer, B., Gholipour, A., Warfield, S.K.: Super-resolution reconstruction to increase the spatial resolution of diffusion weighted images from orthogonal anisotropic acquisitions. Med. Image Anal. 16(7), 1465–1476 (2012)

    Article  Google Scholar 

  22. Shi, F., Cheng, J., Wang, L., Yap, P.-T., Shen, D.: Super-resolution reconstruction of diffusion-weighted images using 4D low-rank and total variation. In: Fuster, A., Ghosh, A., Kaden, E., Rathi, Y., Reisert, M. (eds.) Computational Diffusion MRI. MV, pp. 15–25. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-28588-7_2

    Chapter  Google Scholar 

  23. Shi, W., et al.: Real-time single image and video super-resolution using an efficient sub-pixel convolutional neural network. In: Computer Vision and Pattern Recognition (CVPR), pp. 1874–1883 (2016)

    Google Scholar 

  24. Sotiropoulos, S.N., et al.: Advances in diffusion MRI acquisition and processing in the human connectome project. NeuroImage 80, 125–143 (2013)

    Article  Google Scholar 

  25. Van Steenkiste, G., et al.: Super-resolution reconstruction of diffusion parameters from diffusion-weighted images with different slice orientations. Magn. Reson. Med. 75(1), 181–195 (2016)

    Article  Google Scholar 

  26. Yap, P.T., Zhang, Y., Shen, D.: Multi-tissue decomposition of diffusion MRI signals via \(\ell _ {0}\) sparse-group estimation. IEEE Trans. Image Process. 25(9), 4340–4353 (2016)

    MathSciNet  MATH  Google Scholar 

  27. Ye, C., Zhuo, J., Gullapalli, R.P., Prince, J.L.: Estimation of fiber orientations using neighborhood information. Med. Image Anal. 32, 243–256 (2016)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Pew-Thian Yap or Dinggang Shen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Hong, Y., Chen, G., Yap, PT., Shen, D. (2019). Multifold Acceleration of Diffusion MRI via Deep Learning Reconstruction from Slice-Undersampled Data. In: Chung, A., Gee, J., Yushkevich, P., Bao, S. (eds) Information Processing in Medical Imaging. IPMI 2019. Lecture Notes in Computer Science(), vol 11492. Springer, Cham. https://doi.org/10.1007/978-3-030-20351-1_41

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-20351-1_41

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-20350-4

  • Online ISBN: 978-3-030-20351-1

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics