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Current State of Platinum Complexes for the Treatment of Advanced and Drug-Resistant Breast Cancers

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Breast Cancer Metastasis and Drug Resistance

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1152))

Abstract

Breast cancer represents the major cause of death in female cancer patients. New efficient treatments are desperately needed, particularly especially for patients suffering from advanced stages and metastases, or those who are no longer responding to the clinically established drugs such as cisplatin or carboplatin. New promising therapy regimens and platinum complexes have emerged over the last few years that displayed efficacy in advanced platinum- and/or drug-resistant breast tumors and metastases. This chapter provides an overview of the latest developments in the field of platinum-based drugs against advanced and resistant breast cancers since 2013.

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Acknowledgments

Own work referenced in this chapter was supported by grants from the Deutsche Forschungsgemeinschaft (Scho 402/8 and Scho 402/12).

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  1. Organic Chemistry Laboratory, Bayreuth, Germany

    Bernhard Biersack & Rainer Schobert

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  1. Bernhard Biersack
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  1. Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA

    Aamir Ahmad

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Biersack, B., Schobert, R. (2019). Current State of Platinum Complexes for the Treatment of Advanced and Drug-Resistant Breast Cancers. In: Ahmad, A. (eds) Breast Cancer Metastasis and Drug Resistance. Advances in Experimental Medicine and Biology, vol 1152. Springer, Cham. https://doi.org/10.1007/978-3-030-20301-6_13

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