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Management of Urologic Complications Following Metoidioplasty and Phalloplasty

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Urological Care for the Transgender Patient

Abstract

Transmasculine genital reconstructive surgery is an important part of gender affirmation for many transgender men. Metoidioplasty and phalloplasty are the two genital reconstructive options that exist for the creation of a neophallus. The unique anatomy of the neophallic urethra and specific surgical steps in its construction can lead to several urologic complications, including urethrocutaneous fistulas, persistent vaginal cavities, and urethral strictures. The role of a urologist in evaluating and treating these complications is imperative.

This chapter will discuss the urologic complications following genital reconstructive surgery in addition to the surgical techniques that can be used to manage these complications.

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References

  1. Wernick JA, Busa S, Matouck K, et al. A systematic review of the psychological benefits of gender-affirming surgery. Urol Clin N Am. 2019;46:475–86.

    Article  Google Scholar 

  2. Hage JJ, Karim RB. Ought GIDNOS get nought? Treatment options for nontranssexual gender dysphoria. Plast Reconstr Surg. 2000;105(3):1222–7.

    Article  CAS  PubMed  Google Scholar 

  3. Giami A, Beaubatie E. Gender identification and sex reassignment surgery in the trans population: a survey study in France. Arch Sex Behav. 2014;43:1491–501.

    Article  PubMed  Google Scholar 

  4. James SE, Herman JL, Rankin S, et al. The report of the 2015 U.S. transgender survey. Washington, DC: National Center for Transgender Equality; 2016.

    Google Scholar 

  5. Kailas M, Lu H, Rothman E, et al. Prevalence and types of gender-affirming surgery among a sample of transgender endocrinology patients prior to state expansion of insurance coverage. Endocr Pract. 2017;23(7):780–6.

    Article  PubMed  Google Scholar 

  6. Dy GW, Sun J, Granieri MA, et al. Reconstructive management pearls for the transgender patient. Curr Urol Rep. 2018;19:36.

    Article  PubMed  Google Scholar 

  7. Nolan IT, Dy GW, Levitt N. Considerations in gender-affirming surgery. Urol Clin N Am. 2019;46:459–65.

    Article  Google Scholar 

  8. Coleman E, Bockting W, Botzer M, et al. Standards of care for the health of transsexual, transgender, and gender-nonconforming people: version 7. Int J Transgend. 2012;13(4):165–232.

    Article  Google Scholar 

  9. Pan S, Honig SC. Gender-affirming surgeferrry: current concepts. Andrology and infertility. Curr Urol Rep. 2018;19:62.

    Article  PubMed  Google Scholar 

  10. Stojanovic B, Bizic M, Bencic M, et al. One-stage gender-confirmation surgery as a viable surgical procedure for female-to-male transsexuals. J Sex Med. 2017;14:741.

    Article  PubMed  Google Scholar 

  11. Garcia MM, Christopher NA, De Luca F, et al. Overall satisfaction, sexual function, and the durability of neophallus dimensions following staged female to male genital gender confirming surgery: the Institute of Urology, London U.K. experience. Transl Androl Urol. 2014;3:156.

    PubMed  PubMed Central  Google Scholar 

  12. World Professional Association for Transgender Health (WPATH). Standards of care for the health of transsexual, transgender, and gender nonconforming people. Version 7. 2011. www.wpath.org/publications/soc. Accessed 5 Dec 2019.

  13. Hage JJ, Bout CA, Bloem JJ, et al. Phalloplasty in female-to-male transsexuals: what do our patients ask for? Ann Plast Surg. 1993;30(4):323–6.

    Article  CAS  PubMed  Google Scholar 

  14. Hage JJ, Bloem JJ. Review of the literature on construction of a neourethra in female-to-male transsexuals. Ann Plast Surg. 1993;30(3):278–86.

    Article  CAS  PubMed  Google Scholar 

  15. Dubin BJ, Sato RM, Laub DR. Results of phalloplasty. Plast Reconstr Surg. 1979;64(2):163–70.

    Article  CAS  PubMed  Google Scholar 

  16. Puckett CL, Montie JE. Construction of male genitalia in the transsexual, using a tubed groin flap for the penis and a hydraulic inflation device. Plast Reconstr Surg. 1978;61(4):523–30.

    Article  CAS  PubMed  Google Scholar 

  17. Morrison SD, Chen ML, Crane CN. An overview of female-to-male gender-confirming surgery. Nat Rev Urol. 2017;14(8):486–500.

    Article  PubMed  Google Scholar 

  18. Ferrando C, Zhao LC, Nikolavsky D. Transgender surgery: female to male. In: Eckler K, editor. UpToDate. Waltham, MA: UpToDate; 2019. www.uptodate.com. Accessed February 9, 2019.

    Google Scholar 

  19. Massie JP, Morrison SD, Wilson SC, et al. Phalloplasty with urethral lengthening: addition of a vascularized bulbospongiosus flap from vaginectomy reduces postoperative urethral complications. Plast Reconstr Surg. 2017;140(4):551.

    Article  CAS  Google Scholar 

  20. Durfee R, Rowland W. Penile substitution with clitoral enlargement and urethral transfer. In: Laub DR, Gandy P, editors. Proceedings of the second interdisciplinary symposium on gender dysphoria syndrome. Standford: Stanford University Press; 1973.

    Google Scholar 

  21. Perovic SV, Djordjevic ML. Metoidioplasty: a variant of phalloplasty in female transsexuals. BJU Int. 2003;92(9):981–5.

    Article  CAS  PubMed  Google Scholar 

  22. Frey JD, Poudrier G, Chiodo MV, Hazen A. A systematic review of metoidioplasty and radial forearm flap Phalloplasty in female-to-male transgender genital reconstruction: is the “ideal” neophallus an achievable goal? Plast Reconstr Surg Glob Open. 2016;4:1131.

    Article  Google Scholar 

  23. Cohanzad S. Extensive metoidioplasty as a technique capable of creating a compatible analogue to a natural penis in female transsexuals. Aesthet Plast Surg. 2016;40:130.

    Article  Google Scholar 

  24. Nikolavsky D, Yamaguchi Y, Levine JP, et al. Urologic sequelae following phalloplasty in transgendered patients. Urol Clin N Am. 2017;44:113–25.

    Article  Google Scholar 

  25. Giles H. Congenital absence of the penis. Br J Plast Surg. 1948;1:8.

    Article  Google Scholar 

  26. Gilbert DA, Horton CE, Terzis JK, et al. New concepts in phallic reconstruction. Ann Plast Surg. 1987;18:128–36.

    Article  CAS  PubMed  Google Scholar 

  27. van der Sluis WB, Smit JM, Pigot GLS, et al. Double flap phalloplasty in transgender men: surgical technique and outcome of pedicled anteriolateral thigh flap phalloplasty combined with radial forearm free flap urethral reconstruction. Microsurgery. 2017;37:917–23.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Namba Y, Watanabe T, Kimata Y. Flap combination phalloplasty in female-to-male transexuals. J Sex Med. 2019;16:934–41.

    Article  PubMed  Google Scholar 

  29. Chang TS, Hwang WY. Forearm flap in one-stage reconstruction of the penis. Plast Reconstr Surg. 1984;74:251–8.

    Article  CAS  PubMed  Google Scholar 

  30. Song R, Gao Y, Song Y, Yu Y, Song Y. The forearm flap. Cin Plast Surg. 1982;9:21–6.

    Article  CAS  Google Scholar 

  31. Monstrey S, Hoebeke P, Selvaggi G, et al. Penile reconstruction: is the forearm flap really the standard technique? Plast Reconstr Surg. 2009;124:510–8.

    Article  CAS  PubMed  Google Scholar 

  32. Garaffa G, Ralph DJ, Christoper N. Total urethral construction with the radial artery-based forearm free flap in the transsexual. BJU Int. 2010;106:1206–10.

    Article  PubMed  Google Scholar 

  33. Lumen N, Monstrey S, Goessaert AS, et al. Urethroplasty for strictures after phallic reconstruction: a single-institution experience. Eur Urol. 2011;60(1):150–8.

    Article  PubMed  Google Scholar 

  34. Rashid M, Tamimy MS. Phalloplasty: the dream and the reality. Indian J Plast Surg. 2013;46(2):283–93.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Al-Tamimi M, Pigot GL, van der Sluis WB, et al. The surgical techniques and outcomes of secondary phalloplasty after metoidioplasty in transgender men: an international, multi-center case series. J Sex Med. 2019;16:1–11.

    Article  Google Scholar 

  36. Schechter LS, Safa B. Introduction to Phalloplasty. Clin Plast Surg. 2018;45:387.

    Article  PubMed  Google Scholar 

  37. Neuville P, Morel-Journel N, Maucourt-Boulch D, et al. Surgical outcomes of erectile implants after phalloplasty: retrospective analysis of 95 procedures. J Sex Med. 2016;13:1758–64.

    Article  Google Scholar 

  38. Remington AC, Morrison SD, Massie JP, et al. Outcomes after phalloplasty: do transgender patients and multiple urethral procedures carry a higher rate of complication? Plast Reconstr Surg. 2018;141:220.

    Article  CAS  Google Scholar 

  39. Ascha M, et al. Outcomes of single stage phalloplasty by pedicled anterolateral thigh flap versus radial forearm free flap in gender confirming surgery. J Urol. 2018;199(1):206–13.

    Article  PubMed  Google Scholar 

  40. Blaschke E, et al. Postoperative imaging of phalloplasties and their complications. Am J Roentgenol. 2014;203:323–8.

    Article  Google Scholar 

  41. Kim SK, Moon JB, Heo J, Kwon YS, Lee KC. A new method of urethroplasty for prevention of fistula in female-to-male gender reassignment surgery. Ann Plast Surg. 2010;64(6):759–64.

    Article  CAS  PubMed  Google Scholar 

  42. Leriche A, Timsit MO, Morel-Journel N, Bouillot A, Dembele D, Ruffion A. Long-term outcome of forearm flee-flap phalloplasty in the treatment of transsexualism. BJU Int. 2008;101(10):1297–300.

    Article  PubMed  Google Scholar 

  43. Rashid M, Sarwar SR. Avulsion injuries of the male external genitalia: classification and reconstruction with the customised radial forearm free flap. Br J Plast Surg. 2005;58(5):585–92.

    Article  PubMed  Google Scholar 

  44. Rohrmann D, Jakse G. Urethroplasty in female-to-male transsexuals. Eur Urol. 2003;44(5):611–4.

    Article  PubMed  Google Scholar 

  45. Schardein JN, Zhao LC, Nikolavsky D. Management of vaginoplasty and phalloplasty complications. Urol Clin N Am. 2019;46:605–18.

    Article  Google Scholar 

  46. Fang RH, Kao YS, Ma S, Lin JT. Phalloplasty in female-to-male transsexuals using free radial osteocutaneous flap: a series of 22 cases. Br J Plast Surg. 1999;52(3):217–22.

    Article  CAS  PubMed  Google Scholar 

  47. Levine LA, Elterman L. Urethroplasty following total phallic reconstruction. J Urol. 1998;160(2):378–82.

    Article  CAS  PubMed  Google Scholar 

  48. Monstrey SJ, Ceulemans P, Hoebeke P. Sex reassignment surgery in the female-to-male transsexual. Semin Plast Surg. 2011;25(3):229–44.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Stowell JT, Grimstad FW, Kirkpatrick DL, et al. Imaging Findings in Transgender Patients after Gender-affirming surgery. Radiographics. 2019;39(5):1368–92.

    Article  PubMed  Google Scholar 

  50. Santucci RA. Urethral complications after transgender phalloplasty: strategies to treat them and minimize their occurrence. Clin Anat. 2018;31(2):187–90.

    Article  PubMed  Google Scholar 

  51. Groenman F, et al. Robot-assisted laparoscopic colpectomy in female-to-male transgender patients; technique and outcomes of a prospective cohort study. Surg Endosc. 2017;31(8):3363–9.

    Article  PubMed  Google Scholar 

  52. Lumen N, Oosterlinck W, Decaestecker K, et al. Endoscopic incision of short (<3 cm) urethral strictures after phallic reconstruction. J Endourol. 2009;23(8):1329–32.

    Article  PubMed  Google Scholar 

  53. Daneshvar M, Hughes M, Nikolavsky D. Surgical management of fossa navicularis and distal urethral strictures. Curr Urol Rep. 2018;19(6):43.

    Article  PubMed  Google Scholar 

  54. Coney BC. A penile flap procedure for the relief of meatal stricture. Br J Urol. 1963;35:182–3.

    Article  Google Scholar 

  55. Blandy JP, Tresidder GC. Meatoplasty. Br J Urol. 1967;39(5):633–4.

    Article  CAS  PubMed  Google Scholar 

  56. Jordan GH. Reconstruction of the fossa navicularis. J Urol. 1987;138(1):102–4.

    Article  CAS  PubMed  Google Scholar 

  57. De Sy WA, Oosterlinck W, Verbaeys A. European experience with 1-stage urethroplasty with free full thickness skin graft. J Urol. 1981;125(4):502–3.

    Article  PubMed  Google Scholar 

  58. Gelman J, Sohn W. 1-stage repair of obliterative distal urethral strictures with buccal graft urethral plate reconstruction and simultaneous onlay penile skin flap. J Urol. 2011;186(3):935–8.

    Article  PubMed  Google Scholar 

  59. Asopa HS, Garg M, Singhal GG, et al. Dorsal free graft urethroplasty for urethral stricture by ventral sagittal urethrotomy approach. Urology. 2001;58(5):657–9.

    Article  CAS  PubMed  Google Scholar 

  60. Chowdhury PS, Nayak P, Mallick S, et al. A single stage ventral onlay buccal mucosal graft urethroplasty for navicular fossa strictures. Indian J Urol. 2014;30(1):17–22.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Goel A, Goel A, Dalela D, Sankhwar SN. Meatoplasty using double buccal mucosal graft technique. Int Utol Nephrol. 2009;41(4):885–7.

    Article  Google Scholar 

  62. Nikolavsky D, Abouelleil M, Daneshvar M. Transurethral ventral buccal mucosa graft inlay urethroplasty for reconstruction of fossa navicularis and distal urethral strictures: surgical technique and preliminary results. In Urol Nephrol. 2016;48(11):1823–9.

    Article  Google Scholar 

  63. Zhang Y, Liu C, Qu C, et al. Is vaginal mucosa graft the excellent substitute material for urethral reconstruction in female-to-male transsexuals? World J Urol. 2015;33:2115–23.

    Article  PubMed  Google Scholar 

  64. Mundy AR, Andrich DE. Entero-urethroplasty for the salvage of bulb-membranous stricture disease or trauma. BJU Int. 2010;105:1716–20.

    Article  PubMed  Google Scholar 

  65. Xu YM, Qiao Y, Sa YL, et al. Urethral reconstruction using colonic mucosa graft for complex strictures. J Urol. 2009;182:1040–3.

    Article  PubMed  Google Scholar 

  66. Vanni AJ. New frontiers in urethral reconstruction: injectables and alternative grafts. Trawl Androl Urol. 2015;4(1):84–91.

    Google Scholar 

  67. Pariser JJ, et al. Buccal mucosal graft urethroplasty for the treatment of urethral stricture in the neophallus. Urology. 2015;85(4):927–31.

    Article  PubMed  Google Scholar 

  68. Palminteri E, Manzoni G, Berdondini E, et al. Combined dorsal plus ventral double buccal mucosa graft in bulbar urethral reconstruction. Eur Urol. 2008;53(1):81–90.

    Article  PubMed  Google Scholar 

  69. Wilson, et al. Fasciocutaneous flap reinforcement of ventral onlay buccal mucosa grafts enables neophallus revision urethroplasty. Ther Adv Urol. 2016;8(6):331–7.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Hoebeke P, Selvaggi G, Ceulemans P, et al. Impact of sex reassignment surgery on lower urinary tract function. Eur Urol. 2005;47(3):398–402.

    Article  PubMed  Google Scholar 

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Correspondence to Jessica Schardein .

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Schardein, J., Blakely, S., Nikolavsky, D. (2021). Management of Urologic Complications Following Metoidioplasty and Phalloplasty. In: Nikolavsky, D., Blakely, S.A. (eds) Urological Care for the Transgender Patient. Springer, Cham. https://doi.org/10.1007/978-3-030-18533-6_11

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  • DOI: https://doi.org/10.1007/978-3-030-18533-6_11

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