Multiple Blisters Over the Dorsum of the Hand

  • Wojciech BaranEmail author
  • Jacek Szepietowski

Practical Points

  • Allergic contact dermatitis is caused by type IV delayed hypersensitivity reaction

  • In the induction phase, contact allergens cross the horny layer of the epidermis and form hapten-protein conjugates, which are presented to T cells by Langerhans cells

  • Activated T cells evolve into dermal memory T cells and trigger acute immune system reaction after next exposure to the allergen, in the elicitation phas


Allergic contact dermatitis Temporary black henna tattoo Delayed-type hypersensitivity reaction 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Dermatology, Venereology and AllergologyWroclaw Medical UniversityWroclawPoland

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