Abdominal Rash and a History of Hirschsprung

  • Mahboubeh MansouriEmail author

Practical Points

  • In contrast to IgE-mediated clinical reaction in food allergy the clinical presentations in Eosinophilic associated gastrointestinal disorders (EGID) are not straight forward and might be misleading

  • Clinical symptoms are variable according to the site and layer of infiltration of eosinophils in esophagus, stomach, duodenum or colon or location of eosinophil infiltration in submucosal, muscular or subserosal layers

  • The diagnosis of EGID needs a high index of suspicion by the physician

  • The diagnosis of EGID should be considered in the presence of any chronic symptoms in the GI tract, with or without atopic diathesis

  • Multiple biopsies depending on site of the involvement, must be taken, in spite of normal look mucosa


Eosinophilic gastrointestinal disorders Protein loosing enteropathy Elimination diet 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Immunology and Allergy, Mofid Children’s HospitalShahid Beheshti University of Medical SciencesTehranIran

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