Recurrent Wheals When He Exercised

  • Makiko Hiragun
  • Shunsuke Takahagi
  • Michihiro HideEmail author

Practical Points

  • This patient with shrimp-associated FDEIA showed hypersensitivity to only the white pacific shrimp

  • Both serum shrimp-sIgE and skin prick test by the commercially available kit and shrimp extract were negative in this patient

  • The hypersensitivity to white pacific shrimp was proved only by the skin prick test utilizing fresh white pacific shrimp meat as is, leading to the diagnosis of shrimp-associated FDEIA

  • Avoidance of exercise for at least 2 h after having the causative food is essential for patients with FDEIA

  • Once life-threatening anaphylaxis occurs, intramuscular epinephrine must be promptly administered regardless of the trigger


Food allergy Food-dependent exercise-induced anaphylaxis Wheat-associated FDEIA Anaphylaxis Intramuscular epinephrine 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Makiko Hiragun
    • 1
  • Shunsuke Takahagi
    • 1
  • Michihiro Hide
    • 1
    Email author
  1. 1.Department of Dermatology, Institute of Biomedical and Health SciencesHiroshima UniversityHiroshimaJapan

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