Vomiting and Angioedema After Eating Chocolate

  • Farzaneh RahmaniEmail author

Practical Points

  • Allergy to nuts is amongst the most common food allergies worldwide

  • Co-allergy to peanut and three nut is common

  • Radioallergosorbent test (RAST) can strongly predict clinical reactivity to peanut

  • Double-blind placebo-controlled oral food challenge is gold-standard in diagnosis of food allergy.


Radioallergosorbent test Peanut Specific IgE Oral food challenge Anaphylaxis 


  1. 1.
    Liu M, Burks AW, Green TD. Tree nut allergy: risk factors for development, mitigation of reaction risk and current efforts in desensitization. Expert Rev Clin Immunol. 2015;11(5):673–9.CrossRefGoogle Scholar
  2. 2.
    Smeekens JM, Bagley K, Kulis M. Tree nut allergies: allergen homology, cross-reactivity, and implications for therapy. Clin Exp Allergy. 2018;48(7):762–72.CrossRefGoogle Scholar
  3. 3.
    Stiefel G, Anagnostou K, Boyle RJ, Brathwaite N, Ewan P, Fox AT, Huber P, Luyt D, Till SJ, Venter C, Clark AT. BSACI guideline for the diagnosis and management of peanut and tree nut allergy. Clin Exp Allergy. 2017;47(6):719–39.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Students Scientific Research Center (SSRC)Tehran University of Medical SciencesTehranIran
  2. 2.NeuroImaging Network (NIN)Universal Scientific Education and Research Network (USERN)TehranIran

Personalised recommendations