Skip to main content
SpringerLink
Log in

Zeolite Microneedles: Recent Advancements and Implications in the Delivery of Collagen

  • Conference paper
  • First Online:
CMBEBIH 2019 (CMBEBIH 2019)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 73))

Included in the following conference series:

  • 2334 Accesses

Abstract

Zeolites are one of the most interesting areas of nanotechnology. They have wide application because of their properties, so they are also used for microneedles for delivery of various drugs. Until now, they have been used for the delivery of insulin, diclofenac and ketoprofen and our work will reveal collagen delivery capabilities and thus the application of zeolite microgels in the application of anti-age preparations based on the comparison of insulin molecule characteristics and collagen molecules. Since it is a preparation that is increasingly used in cosmetology and dermatology, we also find out how the best microneedles made of zeolite are applied for delivery of collagen and explain the application of dermaroller and dermapen with this microneedles.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Iliescu, S.F., Ionescu, D., Petrescu, M., Iliescu, C.: A review on transdermal drug delivery using microneedles: current research and perspective. Ann. Acad. Rom. Sci. Series Sci. Technol. Inf. 7(1), 734 (2014)

    Google Scholar 

  2. Tucak, A.: Mikroiglama posredovana dostava lijekova kroz kožu – Formulacijski aspekti. Unpublished Master Thesis, University of Sarajevo, Sarajevo (2017)

    Google Scholar 

  3. Jha, B., Singh, D.: Basics of zeolites. In: Advanced Structured Materials, pp. 5–31 (2016)

    Google Scholar 

  4. Wong, L., Sun, W., Chan, N., Lai, W., Leung, W., Tsang, J., et al.: Zeolite microneedles for transdermal drug delivery. In: Zeolites to Porous MOF Materials—The 40th Anniversary of International Zeolite Conference, Proceedings of the 15th International Zeolite Conference, pp. 525–530 (2007)

    Chapter  Google Scholar 

  5. Pina, M.P., Mallada, R., Arruebo, M., Urbiztondo, M., Navascués, N., de la Iglesia, O., Santamaria, J.: Zeolite films and membranes. Emerging applications nanoscience. Institute of Aragon, University of Zaragoza, 50009 Zaragoza, Spain

    Google Scholar 

  6. Defect-free zeolite membrane. Membr. Technol. 1998(104), 13 (1998)

    Google Scholar 

  7. Hovhannisyan, V., Dong, C., Lai, F., Chang, N., Chen, S.: Natural zeolite for adsorbing and release of functional materials. J. Biomed. Opt. 23(09), 1 (2018)

    Article  Google Scholar 

  8. Andronikashvili, T., Pagava, K., Kurashvili, T., Eprikashvili, L.: Possibility of application of natural zeolites for medicinal purposes. Bull. Georgian Nat. Acad. Sci. 3(2), 158–167 (2009)

    Google Scholar 

  9. Jacobs, P., Martens, J.: Synthesis of High-Silica Aluminosilicate Zeolites, 1st edn. Elsevier, Amsterdam (1987)

    Google Scholar 

  10. Cerri, G., Farina, M., Brundu, A., Daković, A., Giunchedi, P., Gavini, E., et al.: Natural zeolites for pharmaceutical formulations: preparation and evaluation of a clinoptilolite-based material. Microporous Mesoporous Mater. 223, 58–67 (2016)

    Article  Google Scholar 

  11. Poon, T.: Zeolite microneedles: fabrication, mechanics and transdermal drug delivery. M. Phil Thesis, Hong Kong University of Science and Technology (2013)

    Google Scholar 

  12. Wong, L.: Molecular delivery system based on the nanoporous zeolite microstructures. M. Phil Thesis, Hong Kong University of Science and Technology (2006)

    Google Scholar 

  13. Bacakova, L., Vandrovcova, M., Kopova, I., Jirka, I.: Applications of zeolites in biotechnology and medicine—a review. Biomater. Sci. 6(5), 974–989 (2018)

    Article  Google Scholar 

  14. Sim, V., Poon, H.Y., Wong, W., Chau, L.Y.K., Han, W., Kwan, S.M., et al.: Zeolite microneedle: design for drug delivery. In: Proceedings of the AIChE Annual Meeting (2013)

    Google Scholar 

  15. Gelse, K.: Collagens—structure, function, and biosynthesis. Adv. Drug Deliv. Rev. 55(12), 1531–1546 (2003)

    Article  Google Scholar 

  16. Derewenda, U., Derewenda, Z., Dodson, G., Hubbard, R., Korber, F.: Molecular structure of insulin: the insulin monomer and its assembly. Br. Med. Bull. 45(1), 4–18 (1989)

    Article  Google Scholar 

  17. Shorten, P., McMahon, C., Soboleva, T.: Insulin transport within skeletal muscle transverse tubule networks. Biophys. J. 93(9), 3001–3007 (2007)

    Article  Google Scholar 

  18. Sun, W., Inayathullah, M., Manoukian, M., Malkovskiy, A., Manickam, S., Marinkovich, M., et al.: Transdermal delivery of functional collagen via Polyvinylpyrrolidone Microneedles. Ann. Biomed. Eng. 43(12), 2978–2990 (2015)

    Article  Google Scholar 

  19. Barbosa, G., Debone, H., Severino, P., Souto, E., da Silva, C.: Design and characterization of chitosan/zeolite composite films—effect of zeolite type and zeolite dose on the film properties. Mater. Sci. Eng. C. 60, 246–254 (2016)

    Article  Google Scholar 

  20. Tsioris, K., Raja, W., Pritchard, E., Panilaitis, B., Kaplan, D., Omenetto, F.: Fabrication of silk microneedles for controlled-release drug delivery. Adv. Funct. Mater. 22(2), 330–335 (2011)

    Article  Google Scholar 

  21. Faraji, D., Jahandideh, A., Asghari, A., Akbarzadeh, A., Hesaraki, S.: Effect of zeolite and zeolite/collagen nanocomposite scaffolds on healing of segmental femur bone defect in rabbits. Iran. J. Vet. Surg. 12(2), 63–69 (2017)

    Google Scholar 

  22. Kochhar, J., Anbalagan, P., Shelar, S., Neo, J., Iliescu, C., Kang, L.: Direct microneedle array fabrication off a photomask to deliver collagen through skin. Pharm. Res. 31(7), 1724–1734 (2014)

    Article  Google Scholar 

  23. McCrudden, M., McAlister, E., Courtenay, A., González-Vázquez, P., RajSingh, T., Donnelly, R.: Microneedle applications in improving skin appearance. Exp. Dermatol. 24(8), 561–566 (2015)

    Article  Google Scholar 

  24. Park, K., Kwon, H., Lee, C., Kim, D., Yoon, J., Kim, M., et al.: Efficacy and safety of a new microneedle patch for skin brightening: a Randomized, split-face, single-blind study. J. Cosmet. Dermatol. 16(3), 382–387 (2017)

    Article  Google Scholar 

  25. Jung, H.: Microneedle: the future of pharmaceutical and cosmeceutical delivery systems. J. Pharm. Drug Deliv. Res. 06(03), 1 (2017)

    Article  Google Scholar 

Download references

Conflict of Interest

Authors have no conflicts of interest to disclose.

Author information

Authors and Affiliations

  1. Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000, Sarajevo, Bosnia and Herzegovina

    Amar Ramović, Zerina Zorlak, Đenana Husić & Samir Ramić

Authors
  1. Amar Ramović
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zerina Zorlak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Đenana Husić
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Samir Ramić
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zerina Zorlak .

Editor information

Editors and Affiliations

  1. International Burch University, Sarajevo, Bosnia and Herzegovina

    Almir Badnjevic

  2. Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina

    Ranko Škrbić

  3. International Burch University, Sarajevo, Bosnia and Herzegovina

    Lejla Gurbeta Pokvić

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Ramović, A., Zorlak, Z., Husić, Đ., Ramić, S. (2020). Zeolite Microneedles: Recent Advancements and Implications in the Delivery of Collagen. In: Badnjevic, A., Škrbić, R., Gurbeta Pokvić, L. (eds) CMBEBIH 2019. CMBEBIH 2019. IFMBE Proceedings, vol 73. Springer, Cham. https://doi.org/10.1007/978-3-030-17971-7_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-17971-7_39

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17970-0

  • Online ISBN: 978-3-030-17971-7

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics

Search

Navigation