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The Hydrogenosome Is Born: In Memoriam Donald G. Lindmark

  • Miklós MüllerEmail author
Chapter
Part of the Microbiology Monographs book series (MICROMONO, volume 9)

Abstract

The first version of this multi-author work devoted to hydrogenosomes and mitosomes, younger cousins of the well-known mitochondria, was published 10 years ago (Tachezy 2008). Although Eduard, the hero of Goethe’s novel, lamented already in 1807 that one “had to relearn everything every five years,” the publication of a new edition, although not 5 but only 10 years later, still indicates a significant increase of our knowledge and understanding of these organelles.

Notes

Acknowledgments

My research could not have unfolded without the generous support of those who accommodated me in their Departments and laboratories: Imre Törő and Béla Párducz in Budapest, Christian de Duve and William Trager in New York, Heinz Holter and Cicily Chapman-Andresen in Copenhagen, André Adoutte and Hervé le Guyader in Orsay, and William Martin in Düsseldorf. I am indebted to all. My wife and parasitologist colleague Jan S. Keithly stood by me for long, long years. Many colleagues participated in our work, to many to be listed here. Their contributions are acknowledged in the individual papers, which emerged from this work. Much of the work was supported with past grants from NIH and NSF.

References

  1. Brugerolle G, Metenier G (1973) Localisaion intracellulaire et characterization des deux types de malate déshydrogénase chez Trichomonas vaginalis Donné. J Protozool 20:320–327CrossRefGoogle Scholar
  2. Čerkasov J, Čerkasovová A, Kulda J, Vilhelmová D (1978) Respiration of hydrogenosomes of Tritrichomonas foetus. I. J Biol Chem 253:1207–1214PubMedGoogle Scholar
  3. de Duve C (1969) Evolution of the peroxisome. Ann N Y Acad Sci 168:369–381CrossRefGoogle Scholar
  4. Jaroll EL (2014) In memoriam: Donald G. Lindmark (1942-2013). J Eukaryot Microbiol 61:446–447CrossRefGoogle Scholar
  5. Lindmark DG, Müller M (1973) Hydrogenosome, a cytoplasmic organelle of the anaerobic flagellate Tritrichomonas foetus, and its role in pyruvate metabolism. J Biol Chem 248:7724–7728PubMedGoogle Scholar
  6. Müller M (1967) Digestion. In: Florkin M, Scheer BT, Kidder GW (eds) Chemical zoology, vol 1 Protozoa. Academic, New York, pp 351–380Google Scholar
  7. Müller M (1973) Cytology of trichomonad flagellates. I. Subcellular localization of hydrolases, dehydrogenases, and catalase in Tritrichomonas foetus. J Cell Biol 57:453–474CrossRefGoogle Scholar
  8. Müller M (1985) Search for cell organelles in protozoa. J Protozool 32:59–563CrossRefGoogle Scholar
  9. Müller M (2007) The road to hydrogenosomes. In: Martin WF, Müller M (eds) Origin of mitochondria and hydrogenosomes. Springer, Berlin, pp 1–11Google Scholar
  10. Müller M (2012) Discovering the hydrogenosome. In: Moberg CL (ed) Entering an unseen world. A founding laboratory and origins of modern cell biology 1910-1914. The Rockefeller University Press, New York, pp 305–309Google Scholar
  11. Tachezy J (ed) (2008) Hydrogenosomes and mitosomes: mitochondria of anaerobic eukaryotes. Springer, BerlinGoogle Scholar
  12. Tovar J, Fischer A, Clark CG (1999) The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica. Mol Microbiol 32:1013–1021CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.The Rockefeller UniversityNew YorkUSA

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