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HLA Class-II Expression in Human Tumors

  • Federico Garrido
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1151)

Abstract

HLA class II molecules play a pivotal role in antigen presentation to T lymphocytes. This chapter analyzed the expression of these molecules in different human tumors and their role in cancer progression. The possible connection between tumor HLA class II expression and the pathogenesis of autoimmune diseases is discussed.

Keywords

HLA-II in tissues HLA-II in tumors Antigen presenting cells Interferon Tumor rejection Tumor prognosis HLA-II & autoimmunity Immunohistochemistry Tumor infiltrating lymphocytes Cytokynes 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Federico Garrido
    • 1
  1. 1.Departamento de Analisis Clinicos e Inmunologia, Hospital Universitario Virgen de las Nieves, Facultad de MedicinaUniversidad de GranadaGranadaSpain

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