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Management of Infection Stones

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The Role of Bacteria in Urology

Abstract

Infection stones are the result of urinary changes secondary to chronic bacterial infection with a urease splitting organism. If left untreated infection stones can result in significant morbidity and even death from sepsis. Traditionally, treatment has included complete stone removal and culture specific antibiotic therapy to rid the underlying infection. Percutaneous nephrolithotomy is the mainstay of surgical treatment; however, robotic pelvilithotomy and ureteroscopy are emerging as alternative therapies. In this chapter we will cover the pros and cons of different treatment approaches for infection stones.

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References

  1. Daudon M, Dore JC, Jungers P, et al. Changes in stone composition according to age and gender of patients: a multivariate epidemiological approach. Urol Res. 2004;32(3):241–7. https://doi.org/10.1007/s00240-004-0421-y. [published Online First: 2004/05/06].

    Article  PubMed  Google Scholar 

  2. Englert KM, McAteer JA, Lingeman JE, et al. High carbonate level of apatite in kidney stones implies infection, but is it predictive? Urolithiasis. 2013;41(5):389–94. https://doi.org/10.1007/s00240-013-0591-6. [published Online First: 2013/07/25].

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Viprakasit DP, Sawyer MD, Herrell SD, et al. Changing composition of staghorn calculi. J Urol. 2011;186(6):2285–90. https://doi.org/10.1016/j.juro.2011.07.089. [published Online First: 2011/10/22].

    Article  PubMed  Google Scholar 

  4. De Cógáin MR, Lieske JC, Vrtiska TJ, et al. Secondarily infected nonstruvite urolithiasis: a prospective evaluation. Urology. 2014;84(6):1295–300.

    Article  PubMed  Google Scholar 

  5. Flannigan R, Choy WH, Chew B, et al. Renal struvite stones – pathogenesis, microbiology, and management strategies. Nat Rev Urol. 2014;11(6):333–41. https://doi.org/10.1038/nrurol.2014.99. [published Online First: 2014/05/14].

    Article  CAS  PubMed  Google Scholar 

  6. Deutsch PG, Subramonian K. Conservative management of staghorn calculi: a single-centre experience. BJU Int. 2016;118(3):444–50. https://doi.org/10.1111/bju.13393. [published Online First: 2015/12/15].

    Article  PubMed  Google Scholar 

  7. Schwartz BF, Stoller ML. Nonsurgical management of infection-related renal calculi. Urol Clin N Am. 1999;26(4):765–78, viii. [published Online First: 1999/12/10].

    Article  CAS  Google Scholar 

  8. Preminger GM, Assimos DG, Lingeman JE, et al. Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations. J Urol. 2005;173(6):1991–2000. [published Online First: 2005/05/10].

    Article  PubMed  Google Scholar 

  9. Assimos D, Krambeck A, Miller NL, et al. Surgical management of stones: American urological association/endourological society guideline, part II. J Urol. 2016;196(4):1161–9.

    Article  PubMed  Google Scholar 

  10. Koga S, Arakaki Y, Matsuoka M, et al. Staghorn calculi – long-term results of management. Br J Urol. 1991;68(2):122–4. [published Online First: 1991/08/01].

    Article  CAS  PubMed  Google Scholar 

  11. Blandy JP, Singh M. The case for a more aggressive approach to staghorn stones. J Urol. 1976;115(5):505–6. [published Online First: 1976/05/01].

    Article  CAS  PubMed  Google Scholar 

  12. Morgan TN, Shahait M, Maganty A, et al. Conservative management of staghorn calculi: when is it safe? J Endourol Endourol Soc. 2018;32(6):541–5. https://doi.org/10.1089/end.2018.0002. [published Online First: 2018/03/03].

    Article  Google Scholar 

  13. Bernardo NO, Smith AD. Chemolysis of urinary calculi. Urol Clin N Am. 2000;27(2):355–65. [published Online First: 2000/04/25].

    Article  CAS  Google Scholar 

  14. Diri A, Diri B. Management of staghorn renal stones. Ren Fail. 2018;40(1):357–62. https://doi.org/10.1080/0886022x.2018.1459306. [ published Online First: 2018/04/17].

    Article  PubMed  PubMed Central  Google Scholar 

  15. Dretler SP, Pfister RC. Percutaneous dissolution of renal calculi. Annu Rev Med. 1983;34:359–66. https://doi.org/10.1146/annurev.me.34.020183.002043. [published Online First: 1983/01/01].

    Article  CAS  PubMed  Google Scholar 

  16. Griffith DP, Gleeson MJ, Lee H, et al. Randomized, double-blind trial of Lithostat (acetohydroxamic acid) in the palliative treatment of infection-induced urinary calculi. Eur Urol. 1991;20(3):243–7. [published Online First: 1991/01/01].

    Article  CAS  PubMed  Google Scholar 

  17. Williams JJ, Rodman JS, Peterson CM. A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis. N Engl J Med. 1984;311(12):760–4. https://doi.org/10.1056/nejm198409203111203. [published Online First: 1984/09/20].

    Article  CAS  PubMed  Google Scholar 

  18. Iqbal MW, Youssef RF, Neisius A, et al. Contemporary management of struvite stones using combined endourologic and medical treatment: predictors of unfavorable clinical outcome. J Endourol Endourol Soc. 2016;30(7):771–7. https://doi.org/10.1089/end.2013.0257. [published Online First: 2013/11/21].

    Article  Google Scholar 

  19. Türk C, Knoll T, et al. European association of urology guidelines on urolithiasis. Eur Urol. 2016;69(3):475–82.

    Google Scholar 

  20. Lam HS, Lingeman JE, Barron M, et al. Staghorn calculi: analysis of treatment results between initial percutaneous nephrostolithotomy and extracorporeal shock wave lithotripsy monotherapy with reference to surface area. J Urol. 1992;147(5):1219–25. [published Online First: 1992/05/01].

    Article  CAS  PubMed  Google Scholar 

  21. Marguet CG, Springhart WP, Tan YH, et al. Simultaneous combined use of flexible ureteroscopy and percutaneous nephrolithotomy to reduce the number of access tracts in the management of complex renal calculi. BJU Int. 2005;96(7):1097–100. https://doi.org/10.1111/j.1464-410X.2005.05808.x. [published Online First: 2005/10/18].

    Article  PubMed  Google Scholar 

  22. Wong C, Leveillee RJ. Single upper-pole percutaneous access for treatment of > or = 5-cm complex branched staghorn calculi: is shockwave lithotripsy necessary? J Endourol Endourol Soc. 2002;16(7):477–81. https://doi.org/10.1089/089277902760367430. [published Online First: 2002/10/25].

    Article  Google Scholar 

  23. Skolarikos A, Papatsoris AG. Diagnosis and management of postpercutaneous nephrolithotomy residual stone fragments. J Endourol Endourol Soc. 2009;23(10):1751–5. https://doi.org/10.1089/end.2009.1546. [published Online First: 2009/09/15].

    Article  Google Scholar 

  24. Al-Kohlany KM, Shokeir AA, Mosbah A, et al. Treatment of complete staghorn stones: a prospective randomized comparison of open surgery versus percutaneous nephrolithotomy. J Urol. 2005;173(2):469–73. https://doi.org/10.1097/01.ju.0000150519.49495.88. [published Online First: 2005/01/12].

    Article  PubMed  Google Scholar 

  25. Bai Y, Tang Y, Deng L, et al. Management of large renal stones: laparoscopic pyelolithotomy versus percutaneous nephrolithotomy. BMC Urol. 2017;17(1):75. https://doi.org/10.1186/s12894-017-0266-7. [published Online First: 2017/09/02].

    Article  PubMed  PubMed Central  Google Scholar 

  26. Ghani KR, Rogers CG, Sood A, Kumar R, et al. Robot-assisted anatrophic nephrolithotomy with renal hypothermia for managing staghorn calculi. J Endourol. 2013;27(11):1393–8. (1557-900X (Electronic)).

    Article  PubMed  Google Scholar 

  27. Benson AD, Juliano TM, Miller NL. Infectious outcomes of nephrostomy drainage before percutaneous nephrolithotomy compared to concurrent access. J Urol. 2014;192(3):770–4. (1527-3792 (Electronic)).

    Article  PubMed  Google Scholar 

  28. Bag S, Kumar S, Taneja N, Sharma V, et al. One week of nitrofurantoin before percutaneous nephrolithotomy significantly reduces upper tract infection and urosepsis: a prospective controlled study. Urology. 2011;77:45–9. (1527-9995 (Electronic)).

    Article  PubMed  Google Scholar 

  29. Paonessa J, Gnessin E, Bhojani N, Williams J, Lingeman J. Preoperative bladder urine culture as a predictor of intraoperative stone culture results: clinical implications and relationship to stone composition. J Urol. 2016;196(3):769–74. https://doi.org/10.1016/j.juro.2016.03.148.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Potretzke AM, Park AM, Bauman TM, et al. Is extended preoperative antibiotic prophylaxis for high-risk patients necessary before percutaneous nephrolithotomy? Invest Clin Urol. 2016;57(6):417–23. https://doi.org/10.4111/icu.2016.57.6.417. [published Online First: 2016/11/17].

    Article  Google Scholar 

  31. Astroza G, Lipkin M, Neisius A, et al. Effect of supine vs prone position on outcomes of percutaneous nephrolithotomy in staghorn calculi: results from the Clinical Research Office of the Endourology Society Study. Urology. 2013;82(6):1240–5. https://doi.org/10.1016/j.urology.2013.06.068.

    Article  PubMed  Google Scholar 

  32. De Sio M, Autorino R, Quarto G, et al. Modified supine versus prone position in percutaneous nephrolithotomy for renal stones treatable with a single percutaneous access: a prospective randomized trial. Eur Urol. 2008;54(1):196–202. https://doi.org/10.1016/j.eururo.2008.01.067. [published Online First: 2008/02/12].

    Article  PubMed  Google Scholar 

  33. Zhong W, Zeng G, Wu K, Li X, et al. Does a smaller tract in percutaneous nephrolithotomy contribute to high renal pelvic pressure and postoperative fever? J Endourol. 2008;22:2147–51. (1557-900X (Electronic)).

    Article  PubMed  Google Scholar 

  34. Michel MS, Trojan L, Rassweiler JJ. Complications in percutaneous nephrolithotomy. Eur Urol. 2007;51(4):899–906; discussion 06. https://doi.org/10.1016/j.eururo.2006.10.020 [published Online First: 2006/11/11].

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Indiana University, Indianapolis, IN, USA

    Tim Large

  2. Indiana University/IU Health Physicians, Indianapolis, IN, USA

    Amy E. Krambeck

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  1. Tim Large
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  2. Amy E. Krambeck
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Correspondence to Amy E. Krambeck .

Editor information

Editors and Affiliations

  1. University of British Columbia, The Stone Centre at Vancouver General Hospital, Jack Bell Research Centre, Vancouver, BC, Canada

    Dirk Lange

  2. University of British Columbia, The Stone Centre at Vancouver General Hospital, Jack Bell Research Centre, Vancouver, BC, Canada

    Kymora B. Scotland

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Large, T., Krambeck, A.E. (2019). Management of Infection Stones. In: Lange, D., Scotland, K. (eds) The Role of Bacteria in Urology. Springer, Cham. https://doi.org/10.1007/978-3-030-17542-9_7

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  • DOI: https://doi.org/10.1007/978-3-030-17542-9_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17541-2

  • Online ISBN: 978-3-030-17542-9

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