Mind-Body Wellness Program Benefits

  • Nicholas L. DePace
  • Joseph Colombo


To ensure that the supplements recommended with the Mind-Body Wellness Program do not add to stress through contraindications, the contraindications are described. For example, alpha-lipoic acid may lower resting blood pressure, contraindicating it for patients with low resting pressure. The recommended supplements and lifestyles form this kernel of a Wellness Program. The weight of scientifically rigorous and statistically significant evidence behind this program is brought to bear in this chapter as it subserves functional medicine as well as clinical medicine. For example, additions to this kernel that help to tailor the program to specific conditions are presented. For example, by adding cannabidiol, the program is customized for pain management (including fibromyalgia) or anxiety. Neurofeedback is also introduced as another means of treating P&S imbalance, as an adjunct to the program.

A series of quality of life questionnaires, specific for autonomic dysfunction conditions (e.g., diabetes, Ehlers-Danlos syndrome, and autonomic neuropathy), are presented to help in the clinic with diagnoses and therapy planning. To further support therapy planning, examples of the program’s application to various therapies and diseases are discussed, including: (1) evidence that supplements and nutraceuticals, augmented by the program, help to improve pharmacology in those patients that respond to the nutraceuticals (i.e., omega-3s help to close the Statin Gap and help to treat atherosclerosis); (2) evidence that various antioxidant treatments, augmented by the program, may treat atrial fibrillation or neurogenic orthostatic hypotension; (3) evidence that the program treats anxiety, depression-anxiety syndromes, PTSD, ADD/ADHD, some forms of migraine headache, chronic fatigue, and persistent fatigue by helping to restore and establish proper brain perfusion and energy production; (4) evidence that reducing stress (both oxidative and psychosocial) as part of the program helps to treat autonomic dysfunction and small fiber neuropathy, as well as cardiovascular diseases and cancer (including breast cancer); (5) forms of hypertension, specifically, hypertension secondary to parasympathetic excess and hypertension secondary to orthostatic dysfunction, are presented with therapy options; (6) mitochondrial dysfunction associated with neurodegenerative disorders is presented with therapy options; and (7) longevity which is addressed through a discussion of telomere length and its maintenance with the program, including fish oils and antioxidants.


Alpha-lipoic acid Antioxidant Anxiety Atherosclerosis Atrial fibrillation Autonomic dysfunction Beetroot extract Breast cancer B vitamins Cannabidiol Cardiovascular disease Chronic fatigue syndrome Coenzyme Q-10 Congestive heart failure Depression Fibromyalgia Folic acid “Functional medicine” Hypertension L-Arginine L-Carnitine L-Citrulline Longevity Lysine Migraine headaches Mitochondrial dysfunction Neurodegenerative disorders Neurofeedback Omega-3 Fish oil Orthostatic dysfunction Oxidative stress Parasympathetic excess Persistent fatigue Posttraumatic stress disorder Quality of life questionnaires Small fiber neuropathy Supplement contraindications Telomere length 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Nicholas L. DePace
    • 1
  • Joseph Colombo
    • 2
  1. 1.Franklin Cardiovascular Associates, PA and Autonomic Dysfunction and POTS CenterSewellUSA
  2. 2.TMCAMS, Inc.Franklin Cardiovascular Associates, PA and Autonomic Dysfunction and POTS CenterRichboroUSA

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