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Introduction

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Abstract

Drs. DePace and Colombo augmented the Philadelphia Formula for Reversing and Halting Atherosclerosis by adding features that focus on relieving parasympathetic and sympathetic (P&S) dysfunction. Autonomic dysfunction involves any disorder, disease, or malfunction of the ANS, including one or both of its two branches: the P&S nervous systems. Mitochondria dysfunction involves any disorder or disease associated with low energy states (including anxiety secondary to (preclinical) depression). Both mitochondria and the P&S nervous systems effect virtually every cell of the human body, and their proper functioning are considered to be foundational to establishing and maintaining health and wellness. In this chapter the “six-prong” formula is introduced, with its combined (in toto) effect on both mitochondria and the P&S nervous system and thereby its combined effect on the entire body as it subserves health and wellness.

Keywords

  • Autonomic nervous system
  • Brain-heart health
  • Mind-body wellness
  • Mitochondria
  • Parasympathetic nervous system
  • Sympathetic nervous system

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Fig. 1.1

References

  1. DePace NL, Dowinsky SK, Sherman M. The heart repair manual. New York: WW Norton and Co; 1993.

    Google Scholar 

  2. Colombo J, Arora RR, DePace NL, Vinik AI. Clinical autonomic dysfunction: measurement, indications, therapies, and outcomes. New York: Springer Science + Business Media; 2014.

    Google Scholar 

  3. Tsuji H, Venditti FJ Jr, Manders ES, Evans JC, Larson MG, Feldman CL, Levy D. Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study. Circulation. 1994;90(2):878–83.

    CAS  CrossRef  Google Scholar 

  4. D’Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743–53. https://doi.org/10.1161/CIRCULATIONAHA.107.699579. Epub 2008 Jan 22.

    CrossRef  Google Scholar 

  5. DePace NL, Colombo J. Autonomic and mitochondrial dysfunction in clinical diseases: diagnostic, prevention, and therapy. New York: Springer Science + Business Media, Accepted 2019.

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DePace, N.L., Colombo, J. (2019). Introduction. In: Clinical Autonomic and Mitochondrial Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-17016-5_1

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  • DOI: https://doi.org/10.1007/978-3-030-17016-5_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17015-8

  • Online ISBN: 978-3-030-17016-5

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