Microbiota: Novel Gateway Towards Personalised Medicine

Zucko, Jurica; Starcevic, Antonio; Diminic, Janko; Oros, Damir

doi:10.1007/978-3-030-16465-2_9

Microbiota: Novel Gateway Towards Personalised Medicine

Jurica Zucko⁸,
Antonio Starcevic⁸,
Janko Diminic⁸ &
Damir Oros⁸

Chapter
First Online: 03 August 2019

479 Accesses

Part of the Europeanization and Globalization book series (EAG,volume 5)

Abstract

Microbes living in and on us have been recognized in the last decade as important part of ourselves and have been assigned a status of an organ with a wide range of functions—from metabolizing food to training our immune system. The intraindividual and interindividual variation of normal microbiota is vast and its composition is influenced by various external factors—most notable being diet, antibiotics and medication. External factors can cause a disturbance in microbiota frequently termed as dysbiosis which is often associated with a range of diseases—from inflammatory bowel disease and diabetes to obesity and cancer. Pioneering works in manipulating the microbiota for preventing and treating disease shows huge promise but also open a number of questions—from standardization and safety to personalization and reproducibility.

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Notes

1.
Sender et al. (2016).
2.
Qin et al. (2010).
3.
Grice and Segre (2012).
4.
Turnbaugh et al. (2007).
5.
Arumugam et al. (2011).
6.
Knights et al. (2014).
7.
Bien et al. (2013), and Knights et al. (2013).
8.
DeGruttola et al. (2016).
9.
Aagaard et al. (2014).
10.
Dominguez-Bello et al. (2010).
11.
Lozupone et al. (2012).
12.
Koenig et al. (2011).
13.
De Filippo et al. (2010).
14.
Eckburg et al. (2005).
15.
Falony et al. (2016).
16.
David et al. (2014).
17.
Yatsunenko et al. (2012).
18.
Lin et al. (2013).
19.
Ou et al. (2013).
20.
Schnorr et al. (2014).
21.
Becattini et al. (2016).
22.
Jernberg et al. (2010).
23.
Risnes et al. (2011).
24.
Conlon and Bird (2015).
25.
Voreades et al. (2014).
26.
Morton et al. (2015).
27.
Martinez et al. (2015).
28.
Spor et al. (2011).
29.
Blekhman et al. (2015).
30.
Goodrich et al. (2016).
31.
Shanahan and Bernstein (2009).
32.
Marchesi et al. (2015).
33.
Hansen et al. (2012).
34.
Lupp et al. (2007).
35.
Turnbaugh et al. (2006).
36.
Ley et al. (2005).
37.
Ley et al. (2006), and Duncan et al. (2008).
38.
Turnbaugh et al. (2008).
39.
Ridaura et al. (2013).
40.
Qin et al. (2012).
41.
Karlsson et al. (2013).
42.
Schulz et al. (2014).
43.
Sears and Pardoll (2011).
44.
Tjalsma et al. (2012).
45.
Warren et al. (2013).
46.
O'Keefe et al. (2015).
47.
Scott et al. (2015).
48.
Scott et al. (2014).
49.
Sokol et al. (2008).
50.
Sokol et al. (2009).
51.
Ramirez-Farias et al. (2009).
52.
Andrews and Tan (2012).
53.
Kruis et al. (2004).
54.
Hsiao et al. (2013).
55.
Engelbrektson et al. (2009).
56.
Zhang et al. (2015).
57.
Sanchez et al. (2014).
58.
Zhang et al. (2012).
59.
Borody et al. (2004).
60.
Drekonja et al. (2015).
61.
Choi and Cho (2016).
62.
Bakken et al. (2011), and Surawicz et al. (2013).
63.
Brandt and Aroniadis (2013).
64.
Alang and Kelly (2015).
65.
Kazerouni et al. (2015).
66.
Li et al. (2016b).
67.
Kang et al. (2013).
68.
Li et al. (2016a).

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Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia
Jurica Zucko, Antonio Starcevic, Janko Diminic & Damir Oros

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Jurica Zucko
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Antonio Starcevic
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Janko Diminic
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Damir Oros
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Faculty of Law, University of Rijeka, Rijeka, Croatia
Prof. Dr. Nada Bodiroga-Vukobrat
Croatian Academy of Sciences and Arts, Rijeka, Croatia
Prof. Dr. Daniel Rukavina
Juraj Dobrila University of Pula, Faculty of Medicine, Pula, Croatia; Department of Biotechnology, Centre for High-Throughput Technologies, University of Rijeka, Rijeka, Croatia
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University of Applied Sciences, Ludwigsburg, Germany
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Zucko, J., Starcevic, A., Diminic, J., Oros, D. (2019). Microbiota: Novel Gateway Towards Personalised Medicine. In: Bodiroga-Vukobrat, N., Rukavina, D., Pavelić, K., Sander, G. (eds) Personalized Medicine in Healthcare Systems. Europeanization and Globalization, vol 5. Springer, Cham. https://doi.org/10.1007/978-3-030-16465-2_9

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