Abstract
Dental development is a process by which several genes participate. These genes can be thus characterized as having a multifactorial, or complex, mode of inheritance. The identification of these processes was accelerated by the identification of gene mutations which can explain amelogenesis imperfecta, dentinogenesis imperfecta, and dentin dysplasia. This knowledge has been applied to the study of conditions that are multifactorial in nature such as dental caries (both incipient lesions in enamel and deep lesions extending into dentin), enamel hypoplasia (in particular, molar-incisor hypomineralization), erosive tooth wear, and fluorosis.
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Vieira, A.R. (2019). Genetic Basis of Enamel and Dentin Defects. In: Genetic Basis of Oral Health Conditions. Springer, Cham. https://doi.org/10.1007/978-3-030-14485-2_2
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DOI: https://doi.org/10.1007/978-3-030-14485-2_2
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