The primary goal of prostate needle biopsy is to diagnose prostate cancer. Biopsy evaluation also provides important histomorphological data, including histological type, Gleason score, and tumor volume and extent, which are all critical for clinicians to prognosticate and manage patients. In keeping with the current trend of standardization of surgical pathology reports, several international pathology organizations periodically issue recommendations for the reporting of prostate cancer in needle biopsy specimens. The information that must be included in prostate biopsy reports is understandably in flux as our understanding of the pathological and molecular characteristics of prostate cancer expands and diagnosis and treatment of prostate cancer continue to evolve. In addition, the prostate biopsy should be reported in a format that facilitates effective communications between pathologists and clinicians and data archival for future studies.
KeywordsBenign prostate glands Stroma Nonspecific granulomatous prostatitis Atypical adenomatous hyperplasia (adenosis) Prostate-specific antigen High-grade prostatic intraepithelial neoplasia Atypical glands suspicious for cancer Adenocarcinoma Benign prostatic hyperplasia Gleason score Grade group Unfavorable pathology % pattern 4 Tumor volume measurement Core-level reporting Case-level reporting Synoptic reporting
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