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Disorders of the Pancreas

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Part of the Clinical Gastroenterology book series (CG)

Abstract

Although the human immunodeficiency virus (HIV) has not been isolated in pancreatic tissue (Bennett et al. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Elsevier/Saunders, Philadelphia, 2015), infections and inflammatory conditions of the pancreas are common during the course of acquired immunodeficiency syndrome (AIDS) and contribute significantly to its associated morbidity and mortality. HIV infection itself has been associated with an increased risk of clinical pancreatitis, but specific etiologies are broad. These include antiretroviral medications, chemoprophylaxis drugs for opportunistic infections, malignancy, and the virus itself. Similarly, bacterial, viral, fungal, and mycobacterial pathogens can contribute to the acute pancreatic inflammatory conditions. The pancreas can serve as the primary nidus of infection or ultimately be involved after dissemination of opportunistic infections. In addition, one must consider etiologies that are seen in the general population such as gallstones and complications of alcohol and intravenous drug abuse.

Keywords

HIV/AIDS Pancreas Pancreatitis Drug-Induced Pancreatitis Pancreatic abscess 

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Authors and Affiliations

  1. 1.Division of Infectious Diseases, University of Connecticut School of MedicineFarmingtonUSA
  2. 2.Division of Infectious Diseases, Saint Francis Hospital and Medical CenterHartfordUSA

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