Regeneration of Intrabony Defects Utilizing Stem Cells Allograft



Regeneration of intrabony defects remains an important goal in the treatment of periodontitis. Clinical and histologic evidence of periodontal regeneration has been shown for multiple regenerative approaches, including bone replacement grafts, guided tissue regeneration, and biologics. Despite positive results, the search to achieve improved predictability in terms of correction prevalence, defect types, and ability to maintain long-term results continues. In this chapter, we describe the use of stem cell allograft for the correction of intrabony defects and address whether the results can be improved if used in combination with guided tissue regeneration and/or recombinant human platelet-derived growth factor.


Stem cells Intrabony defects Periodontal regeneration Allograft 


Conflict of Interest Statement

No conflicts of interest have been reported by the above authors.


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Division of PeriodontologyUniversity of California, San FranciscoSan FranciscoUSA
  2. 2.CupertinoUSA
  3. 3.San JoseUSA

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