Skip to main content
SpringerLink
Log in

IDDS for Movement Disorders

  • Chapter
  • First Online:
Deer's Treatment of Pain

  • 101 Accesses

Abstract

Advances in medical technology have made intrathecal baclofen therapy a suitable treatment option for patients suffering from a variety of disorders affecting movement, especially spasticity. These patients have typically exhausted conservative therapies, usually including oral baclofen therapy which has either failed to result in clinically significant reductions in spasticity, intolerable baclofen-related side effects (i.e., sedation), or both. Intrathecal drug delivery systems for movement disorders can provide continuous infusions of baclofen for improvement in rigidity and/or spasticity.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Recommended Reading

  1. Adams MM, Hicks AL. Spasticity after spinal cord injury. Spinal Cord. 2005;43:577–86.

    Article  CAS  Google Scholar 

  2. Albright AL, Turner M, Pattisapu JV. Best- practice surgical techniques for intrathecal baclofen therapy. J Neurosurg Pediatr. 2006;104:233–9.

    Article  Google Scholar 

  3. Booster AL, Bennet SE, Bilsky GS, Gudesblatt M, Koebel SF, McManus M, Saulino M. Best practices for Intrathecal Baclofen therapy: screening test. Neuromodulation. 2016;91:616–22.

    Article  Google Scholar 

  4. Boster AL, Adair RL, Gooch JL, Nelson MES, Toomer A, Urquidez J, Saulino M. Best practices for Intrathecal Baclofen therapy: dosing and long-term management. Neuromodulation. 2016;19:623–31.

    Article  Google Scholar 

  5. Follett KA, Naumann CP. A prospective study of catheter-related complications of Intrathecal Drug delivery systems. J Pain Symptom Manag. 2000;19:209–15.

    Article  CAS  Google Scholar 

  6. Furr-Stimming E, Boyle A, Schiess M. Spasticity and Intrathecal Baclofen. Semin Neurol. 2014;34:591–6.

    Article  Google Scholar 

  7. Hill DR, Bowery NG. H-baclofen and H-GABA bind to bicuculline-insensitive GABAB sites in rat brain. Nature. 1981;290:149–52.

    Article  CAS  Google Scholar 

  8. Knutsson E, Lindoblom U, Martensson A. Plasma and cerebrospinal fluid levels of Baclofen (Lioresal) at optimal therapeutic responses in spastic paresis. J Neurol Sci. 1974;23:473–84.

    Article  CAS  Google Scholar 

  9. Lewis KS, Mueller WM. Intrathecal Baclofen for severe spasticity secondary to spinal cord injury. Ann Pharmacother. 1993;27:767–73.

    Article  CAS  Google Scholar 

  10. Penn RD, Kroin JS. Intrathecal Baclofen Alleviates spinal cord spasticity. Lancet. 1984;1(8385):1078.

    Article  CAS  Google Scholar 

  11. Penn RD, Kroin JS. Long-term intrathecal baclofen infusion for treatment of spasticity. J Neurosurg. 1987;66:181–5.

    Article  CAS  Google Scholar 

  12. Ridley B, Rawlins PK. Intrathecal Baclofen therapy: ten steps toward best practice. J Neurosci Nurs. 2006;38:72–82.

    Article  Google Scholar 

  13. Saulino M, Anderson DJ, Doble J, Farid R, Gul F, Konrad P, Boster A. Best practices for Intrathecal Baclofen therapy: troubleshooting. Neuromodulation. 2016;19:632–41.

    Article  Google Scholar 

  14. Saval A, Chiodo A. Intrathecal Baclofen for spasticity management: a comparative analysis of spasticity of spinal vs. cortical origin. J Spinal Cord Med. 2010;33:16–21.

    Article  Google Scholar 

  15. Sheean G, McGuire JR. Spastic hypertonia and movement disorders: pathophysiology, clinical presentation, and quantification. PM R. 2009;1:827–33.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anesthesiology and Perioperative Medicine, Penn State Health/Penn State College of Medicine, Hershey, PA, USA

    Sadie E. Smith

  2. Penn State Milton S. Hershey Medical Center, Hershey, PA, USA

    Bunty J. Shah

Authors
  1. Sadie E. Smith
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bunty J. Shah
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bunty J. Shah .

Editor information

Editors and Affiliations

  1. The Spine and Nerve Center of the Virginias, Charleston, WV, USA

    Timothy R. Deer

  2. Evolve Restorative Center, Santa Rosa, CA, USA

    Jason E. Pope

  3. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA

    Tim J. Lamer

  4. Pain Diagnostics and Interventional Care, Sewickley, PA, USA

    David Provenzano

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Smith, S.E., Shah, B.J. (2019). IDDS for Movement Disorders. In: Deer, T., Pope, J., Lamer, T., Provenzano, D. (eds) Deer's Treatment of Pain. Springer, Cham. https://doi.org/10.1007/978-3-030-12281-2_85

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-12281-2_85

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-12280-5

  • Online ISBN: 978-3-030-12281-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation