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Molecular and Cell Biology of Cancer pp 191–216Cite as

Case Studies: Molecular Pathology Perspective and Impact on Oncologic Patients’ Management

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Abstract

In this chapter you will have a medical perspective of cancer, how it is diagnosed and treated. In particular we focus on the crucial role of pathology assessment for diagnosis/staging and guide patient treatment/management. We will give an historical view of pathology, how it evolved through the centuries from the standard histopathology methods to this new era of molecular analysis. Also, we will generally describe the different treatment options available. Then, through the discussion of three case studies we will illustrate how pathology evaluation (classical and molecular) gives a window to tumor biology, providing a framework for patient treatment and follow-up.

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Author information

Authors and Affiliations

  1. Molecular and Experimental Pathology Laboratory, Champalimaud Foundation, Lisbon, Portugal

    Mireia Castillo-Martin

  2. Champalimaud Clinical Centre, Lisbon, Portugal

    Joana Ribeiro

Authors
  1. Mireia Castillo-Martin
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  2. Joana Ribeiro
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Corresponding authors

Correspondence to Mireia Castillo-Martin or Joana Ribeiro .

Editor information

Editors and Affiliations

  1. Champalimaud Centre for the Unknown, Champalimaud Foundation, Lisbon, Portugal

    Rita Fior

  2. Faculdade de Ciências da Universidade de Lisboa, Lisbon, Portugal

    Rita Zilhão

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Castillo-Martin, M., Ribeiro, J. (2019). Case Studies: Molecular Pathology Perspective and Impact on Oncologic Patients’ Management. In: Fior, R., Zilhão, R. (eds) Molecular and Cell Biology of Cancer. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-11812-9_10

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