Abstract
Narcolepsy is a chronic neurological disease with five domains of symptoms including excessive daytime sleepiness (EDS), cataplexy, hypnagogic/hypnopompic hallucinations, sleep paralysis, and sleep fragmentation. Several overlapping symptoms of schizophrenia and narcolepsy often make it challenging to differentiate between the two conditions. A 23-year-old African American female was diagnosed with schizophrenia based on a two-year history of auditory and visual hallucinations. The patient was referred to a sleep physician for excessive daytime sleepiness. She has been sleepy since her teenage years taking 1–2 naps daily (Epworth sleepiness scale (ESS) was 14). She also complained of occasional sudden loss of muscle tone, which was triggered by strong emotions. In addition, she had episodes of inability to move her body in the morning, feeling as if someone was sitting on her chest. A full “hypersomnia workup” was scheduled including a nocturnal polysomnography (PSG) followed by a multiple sleep latency test (MSLT). The MSLT was positive for narcolepsy with cataplexy, or type 1 narcolepsy. She was prescribed modafinil 200 mg daily for EDS and venlafaxine 75 mg was added for cataplexy. In two weeks her ESS improved from 14 to 8. This case illustrates the potential of narcolepsy being misdiagnosed as schizophrenia in patients who have excessive daytime sleepiness and symptoms mimicing psychosis.
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Maski K, Steinhart E, Williams D, Scammell T, Flygare J, McCleary K, Gow M. Listening to the patient voice in narcolepsy: diagnostic delay, disease burden, and treatment efficacy. J Clin Sleep Med. 2017;13(3):419–25. https://doi.org/10.5664/jcsm.6494.
Talih FR. Narcolepsy presenting as schizophrenia: a literature review and two case reports. Innov Clin Neurosci. 2011;8(4):30–4.
Sansa G, Gavaldà A, Gaig C, Monreal J, Ercilla G, Casamitjana R, Ribera G, Iranzo A, Santamaria J. Exploring the presence of narcolepsy in patients with schizophrenia. BMC Psychiatry. 2016;16:177. https://doi.org/10.1186/s12888-016-0859-9.
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Iqbal, N., Danish, N., Ebrahim, A., Naeem, A., Khawaja, I.S. (2019). A Case of Narcolepsy Misdiagnosed as Schizophrenia. In: Khawaja, I., Hurwitz, T. (eds) Comorbid Sleep and Psychiatric Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-11772-6_7
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DOI: https://doi.org/10.1007/978-3-030-11772-6_7
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