Abstract
Hypersomnia is a symptom of disturbed sleep. Depressive disorders most commonly result in insomnia with fatigue and tiredness but not excessive sleepiness. Hypersomnia with depression is considered a feature of atypical depression and is more common in patients with bipolar disorder or the adolescent/young adult. Hypersomnia becomes clinically significant when the fight against sleepiness results in social and occupational dysfunction. The classic disorder of hypersomnia is narcolepsy with or without the emotionally triggered muscular weakness of cataplexy, although insufficient sleep, circadian misalignment, medication side effect, and sleep disorders such as sleep apnea and idiopathic hypersomnia are other reasons for excessive daytime sleepiness. What follows is a case of a man whose college career was interrupted by hypersomnia, leading to treatment of a presumed depression but subsequent diagnosis of narcolepsy, type II without cataplexy.
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Selected References
Lopez R, Barateau L, Evangelista E, Dauvilliers Y. Depression and hypersomnia: a complex association. Sleep Med Clin. 2017;12(3):395–405.
Barateau L, Lopez R, Franchi JA, Dauvilliers Y. Hypersomnolence, Hypersomnia, and Mood Disorders. Curr Psychiatry Rep. 2017;19(2):13. Review.
American Academy of Sleep Medicine. International classification of sleep disorders, 3rd ed. Darien: American Academy of Sleep Medicine, 2014.
Plante DT, Cook JD, Goldstein MR. Objective measures of sleep duration and continuity in major depressive disorder with comorbid hypersomnolence: a primary investigation with contiguous systematic review and metaanalysis. J Sleep Res. 2017;26(3):255–65. Review.
Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Subjective and objective measures of hypersomnolence demonstrate divergent associations with depression among participants in the Wisconsin Sleep Cohort Study. J Clin Sleep Med. 2016;12(4):571–8.
Asaad T, Sabry W, Rabie M, El-Rassas H. Polysomnographic characteristics of bipolar hypomanic patients: comparison with unipolar depressed patients. J Affect Disord. 2016;191:274–9.
Chung KF, Yu YM, Yeung WF. Correlates of residual fatigue in patients with major depressive disorder: the role of psychotropic medication. J Affect Disord. 2015;186:192–7.
Zamarian L, Högl B, Delazer M, Hingerl K, Gabelia D, Mitterling T, Brandauer E, Frauscher B. Subjective deficits of attention, cognition and depression in patients with narcolepsy. Sleep Med. 2015;16(1):45–51.
Fernandez-Mendoza J, Vgontzas AN, Kritikou I, Calhoun SL, Liao D, Bixler EO. Natural history of excessive daytime sleepiness: role of obesity, weight loss, depression, and sleep propensity. Sleep. 2015;38(3):351–60.
Goldstein AN, Walker MP. The role of sleep in emotional brain function. Annu Rev Clin Psychol. 2014;10:679–708. Review.
Busková J, Kemlink D, Ibarburu V, NevsÃmalová S, Sonka K. Antidepressants substantially affect basic REM sleep characteristics in narcolepsy-cataplexy patients. Neuro Endocrinol Lett. 2015;36(5):430–3.
Cooper JA, Tucker VL, Papakostas GI. Resolution of sleepiness and fatigue: a comparison of bupropion and selective serotonin reuptake inhibitors in subjects with major depressive disorder achieving remission at doses approved in the European Union. J Psychopharmacol. 2014;28(2):118–24.
Seo HJ, Lee BC, Seok JH, Jeon HJ, Paik JW, Kim W, Kwak KP, Han C, Lee KU, Pae CU. An open-label, raterblinded, 8-week trial of bupropion hydrochloride extended-release in patients with major depressive disorder with atypical features. Pharmacopsychiatry. 2013;46(6):221–6.
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Becker, P.M. (2019). Is It Narcolepsy or Depression Making My Patient Sleepy?. In: Khawaja, I., Hurwitz, T. (eds) Comorbid Sleep and Psychiatric Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-11772-6_6
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DOI: https://doi.org/10.1007/978-3-030-11772-6_6
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