Advertisement

The Role of Interventional Procedures in Childhood and Adolescent Headaches-Peripheral Neuromodulation

  • Ishaq Abu-ArafehEmail author
  • Vincenzo Guidetti
Chapter
Part of the Headache book series (HEAD)

Abstract

Some headache disorders can be intractable and fail to respond to conventional medical treatment and psychological interventions. Non-pharmacological interventions may provide a useful alternative for such patients. Electrical nerve stimulation, nerve blockade or trans-cranial magnetic stimulation are potential therapies that have been studied and shown to have a role to play in the management of adult patients with some chronic headache disorders. Stimulation or blockade of greater occipital nerve, trigeminal nerve ganglion or the vagus nerve may also be useful in the management of headache disorders in children. However, the evidence for such strategies is still evolving and mostly based on small open studies.

In this chapter, we will examine the available treatment modalities, their mechanisms of action and their potential use in children and adolescents.

Keywords

Greater occipital nerve Headache Migraine Neuromodulation Transcranial magnetic stimulation Trigeminal nerve 

References

  1. 1.
    Olesen J, Burstein R, Ashina M, Tfelt-Hansen P. Origin of pain in migraine: evidence for peripheral sensitisation. Lancet Neurol. 2009;8:679–90.CrossRefGoogle Scholar
  2. 2.
    Knight YE, Bartsch T, Kaube H, Goadsby PJ. P/Q-type calciumchannel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? J Neurosci. 2002;22:RC213.CrossRefGoogle Scholar
  3. 3.
    Bartsch T, Knight YE, Goadsby PJ. Activation of 5-HT(1B/1D) receptor in the periaqueductal gray inhibits nociception. Ann Neurol. 2004;56:371–81.CrossRefGoogle Scholar
  4. 4.
    Blumenfeld A, Ashkenazi A, Napchan U, Bender SD, Klein BC, Berliner R, Ailani J, Schim J, Friedman DL, Charleston L, Young WB, Robertson CE, Dodick DW, Silberstein SD, Robbins MS. Expert consensus recommendations for the performance of peripheral nerve blocks for headaches – a narrative review. Headache. 2013;53:437–46.CrossRefGoogle Scholar
  5. 5.
    Puledda F, Goadsby PJ, Prabhakar P. Treatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation. J Headache Pain. 2018;19:5.CrossRefGoogle Scholar
  6. 6.
    Gelfand AA, Reide AC, Goadsby PJ. Outcomes of greater occipital nerve injections in pediatric patients with chronic primary headache disorders. Pediatr Neurol. 2014;50(2):135–9.CrossRefGoogle Scholar
  7. 7.
    Chen Y-F, Bramley G, Unwin G, Hanu-Cernat D, Dretzke J, Moore D, Bayliss S, Cummins C, Lilford R. Occipital nerve stimulation for chronic migraine—a systematic review and meta-analysis. PLoS One. 2015;10(3):e0116786.  https://doi.org/10.1371/journal.pone.0116786.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Schoenen J, Coppola G. Efficacy and mode of action of external trigeminal neurostimulation in migraine. Expert Rev Neurother. 2018;18(7):545–55.CrossRefGoogle Scholar
  9. 9.
    Chou DE, Gross GJ, Casadei CH, Yugrakh MS. External trigeminal nerve stimulation for the acute treatment of migraine: open-label trial on safety and efficacy. Neuromodulation. 2017;20:678–83.CrossRefGoogle Scholar
  10. 10.
    Schoenen J, Vandersmissen B, Jeangette S, Herroelen L, Vandenheede M, Gerard P, Magis D. Migraine prevention with a supraorbital transcutaneous stimulator: a randomized controlled trial. Neurology. 2013;80(8):697–704.CrossRefGoogle Scholar
  11. 11.
    Lipton RB, Dodick DW, Silberstein SD, Saper JR, Aurora SK, Pearlman SH, Fischell RE, Ruppel PL, Goadsby PJ. Single-pulse transcranial magnetic stimulation for acute treatment of migrainewith aura: a randomized, double-blind, parallel-group, sham controlled trial. Lancet Neurol. 2010;9:373–80.CrossRefGoogle Scholar
  12. 12.
    Clarke BM, Upton AR, Kamath MV, Al-Harbi T, Castellanos CM. Transcranial magnetic stimulation for migraine: clinical effects. J Headache Pain. 2006;7:341–6.CrossRefGoogle Scholar
  13. 13.
    Starling AJ, Tepper SJ, Marmura MJ, Shamim EA, Robbins MS, Hindiyeh N, Charles AC, Goadsby PJ, Lipton RB, Silberstein SD, Gelfand AA, Chiacchierini RP, Dodick DW. A multicenter, prospective, single arm, open label, observational study of sTMS for migraine prevention (ESPOUSE Study). Cephalalgia. 2018;38(6):1038–48.CrossRefGoogle Scholar
  14. 14.
    Irwin SL, Qubty W, Allen IE, Patniyot I, Goadsby PJ, Gelfand AA, Transcranial Magnetic MAS. Stimulation for migraine preventionin adolescents: a pilot open-label study. Headache. 2018;58:724–31.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Paediatric Neurosciences Unit, Royal Hospital for ChildrenGlasgowUK
  2. 2.“Sapienza” UniversityRomeItaly

Personalised recommendations