Curve Fitting Derivative Method and Its Application in Mouse Growth

  • Zhihua Li
  • Xin ZhaoEmail author
Conference paper
Part of the IFIP Advances in Information and Communication Technology book series (IFIPAICT, volume 545)


[Goal] Exploring change rules of the mouse growth, providing genetic data for the prediction and production of genetic analysis in scientific research and basic data for the standards of laboratory animals. [Method] Mice were weighed at 10 time points, including 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 weeks of age, and the corresponding data were recorded. Both general and derivative methods of Gompertz curve parameter estimation were used to analyze the mice. Then, the parameter values and the fitting degree \( (R^{2} ) \) were calculated. [Result] The derivative method has the highest \( R^{2} \) (0.993734), followed by the three-point method \( R^{2} \) (0.990689). [Conclusion] The derivative method of Gompertz curve parameter estimation has the best effect on mouse fitting and can be used for the estimation and prediction of mouse growth.


Mouse growth Parameter estimation Curve fitting Derivative method 


  1. 1.
    Cheng, L., Lu, X.Y., Wang, Q.Z.: Development and trend analysis of growth and development curve of Hu sheep. Chin. J. Anim. Husb. Vet. Med. 12, 239–243 (2014)Google Scholar
  2. 2.
    Fu, J.: Interspecific mouse growth curve fitting. Zhejiang Anim. Sci. Vet. Med. 2(2), 6–7 (2000)Google Scholar
  3. 3.
    Yang, M.H., Xu, Q., Dai, G.J.: Analysis of three commonly used growth curves for poultry. Chin. Poult. 8(1), 164–166 (2004)Google Scholar
  4. 4.
    Liu, E.Q., He, Y.X., Bai, F.E.: BALB/c mouse growth curve analysis. Beijing Exp. Anim. Sci. 9(1), 15–16 (1992)Google Scholar
  5. 5.
    Wang, J.F., Shi, M.L., Wu, Y.Q.: Determination of growth curve, main organ parameters and physiological and biochemical indexes of GF grade KM mice. Chin. J. Comp. Med. 22(3), 17–22 (2012)Google Scholar
  6. 6.
    Xi, X.X., Cheng, J., Tian, Y.G.: Determination of growth curve and weight of main organs of three SPF mice. Anim. Vet. Med. Heilongjiang Province 1(1), 136–138 (2012)Google Scholar
  7. 7.
    Zheng, M.E., Li, L., Wu, S.L.: Bertalanffy model analysis of six SPF - size mouse growth curves. Lab. Anim. Sci. 8(4), 11–12 (2015)Google Scholar
  8. 8.
    Yang, N.: Analysis on growth curve of quail in different strains. In: The 4th National Symposium on Poultry Symposium (1989)Google Scholar

Copyright information

© IFIP International Federation for Information Processing 2019

Authors and Affiliations

  1. 1.College of Information TechnologyJilin Agricultural UniversityChangchunChina

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