Current Innovations and Future Trends

  • Neeraj Kumar
  • Ravindra Kumar GargEmail author
  • Hardeep Singh Malhotra


Central nervous system fungal infections are common but diagnosis is usually delayed. Advancement in research is leading to new diagnostic and therapeutic tools. Though microscopy and serology are time-tested investigations, advances in polymerase chain reaction techniques will greatly reduce the diagnostic time and specificity. Proteomic profiling and radiological advancement will further ease the diagnostics. Newer innovation in treatment is likely with many agents being tested in phase 1 and phase 2 trials.


Fungal infection Polymerase chain reaction Innovation Antifungals 



Central nervous system


Cerebrospinal fluid


Cryo-scanning transmission electron tomography


Focused ion beam scanning electron microscopy


Loop-mediated isothermal amplification


Matrix-assited laser desorption/ionization time of flight


Magnetic resonance imaging


Polymerase chain reaction


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Neeraj Kumar
    • 1
  • Ravindra Kumar Garg
    • 1
    Email author
  • Hardeep Singh Malhotra
    • 1
  1. 1.Department of NeurologyKing George’s Medical UniversityLucknowIndia

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