Abstract
Nowadays, significant advances have been made in the development of biodegradable polymeric materials for biomedical applications . This study aims to prepare and characterize composite materials based on PLA/PBAT, a biodegradable polymer blend , reinforced with bio-hydroxyapatite (bio-HAp). First, bio-HAp was obtained from eggshell residues by the wet precipitation method. PLA/PBAT blend with 1.5 wt% of bio-HAp was prepared by melt extrusion and injection molding process. Part of composite samples was irradiated with gamma radiation dose of 25 kGy, at room temperature and presence of air. The effects of the bio-HAp addition into the biodegradable blend were investigated by mechanical tests, XRD , DSC , FE-SEM , and cytotoxicity “in vitro” analysis and the correlation between the properties was discussed. In addition, the microbiological tests were carried out at irradiated and non-irradiated composite samples in order to evaluate the efficiency of the radiation dose of 25 kGy at composite materials sterilization.
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References
Marques RD (2011) Obtaining and characterizing polymer blends of poly (lactic-co-glycolic acid) and poly (isoprene) for application as biomaterial. J Polymer Environ 234–241
Muthuraj R, Misra M, Mohanty AK (2014) Biodegradable poly (butylene succinate) and poly (butylene adipate-co-terephthalate) blends: reactive extrusion and performance evaluation. J Polymer Environ 336–349
Kang Y, Chen P, Shi X, Zhang G, Wang C (2018) Preparation of open-porous stereocomplex PLA/PBAT scaffolds and correlation between their morphology, mechanical behavior, and cell compatibility. R Soc Chem 65–75
Moraes MFV (2004) Produção e caracterização de blenda polimérica biodegradável poli(hidroxibutirato)[PHB]/copoliéster alifático aromático para aplicações em embalagens
Adrar S, Habi A, Ajji A, Grohens Y (2018) Synergistic effects in epoxy functionalized graphene and modified organo-montmorillonite PLA/PBAT blends. Appl Clay Sci 12933–12943
Kijchavengkul T, Auras R, Rubino M, Selke S, Ngouajio M, Fernandez T (2010) Biodegradation and hydrolysis rate of aliphatic aromatic polyester. Polymer Degrad Stab 2641–2647
Caliman LB (2011) Síntese e caracterização de hidroxiapatita obtida a partir de casca de ovo de avestruz. Química nova 142–150
Ferreira SW, Costa RMC, Ferreira BRS, Nunes FS (2017) Structural and electronic properties of hydroxyapatite from calculations of first principles. Engevista 194–201
Charlesby A (1960) Atomic Radiation and polymers. Pergamon Press, New York
Abbona F (1996) A XRD and TEM study on the transformation of amorphous calcium phosphate in the presence of magnesium. J Cryst Growth 165:98–105
Al-Itry R, Lamnawar K, Maazouz A (2014) Reactive extrusion of PLA, PBAT with a multi-functional epoxide: physico-chemical and rheological properties. Eur Polymer J 58:90–102
Arruda CL, Magaton M, Bretas RES, Ueki MM (2016) Influence of chain extender on mechanical, thermal and morphological properties of blown films of PLA/PBAT blends. Polym Test 43:27–37
Kang Y, Chen P, Shi X, Zhang G, Wang C (2018) Preparation of open-porous stereocomplex PLA/PBAT scaffolds and correlation between their morphology, mechanical behavior, and cell compatibility. R Soc Chem 8:65–75
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The authors wish to thank CAPES and IPEN for providing the support for this work.
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© 2019 The Minerals, Metals & Materials Society
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Reis, P.R.S., Santana, J.G., Oliveira, R.R., Rangari, V.K., Lourenço, F.R., Moura, E.A.B. (2019). Development of Biocomposite Materials from Biodegradable Polymer and Bio-hydroxyapatite Derived from Eggshells for Biomedical Applications. In: Li, B., et al. Characterization of Minerals, Metals, and Materials 2019. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-030-05749-7_57
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DOI: https://doi.org/10.1007/978-3-030-05749-7_57
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