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Surgery pp 139–147Cite as

Intermittent Episodes of Sweating, Palpitations, and Hypertension

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Abstract

A 34-year-old woman presents with a chief complaint of what she calls “rushes,” intermittent episodes of sweating, headaches, and palpitations lasting for a few minutes and occurring sporadically every few days. These episodes can occur at any time of day and have sometimes awakened her from sleep. She notes that exercise may provoke her symptoms. Past medical history is significant for newly diagnosed hypertension. Her physical exam is remarkable only for hypertension, with a blood pressure of 165/100 mmHg. Her biochemical workup reveals an elevated 24-hour urine metanephrine (1163 mcg/day; normal <400 mcg/day). A dedicated adrenal protocol CT scan shows a 4-cm mass in the right adrenal gland with central cystic change.

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Suggested Reading

  • Brink I, Hoegerle S, Klisch J, Bley TA. Imaging of pheochromocytoma and paraganglioma. Fam Cancer. 2005;4(1):61–8.

    Article  CAS  Google Scholar 

  • Dluhy RG. Pheochromocytoma – death of an axiom. N Engl J Med. 2002;346(19):1486–8.

    Google Scholar 

  • Hodin R, Lubitz C, Phitayakorn R, Stephen A. Diagnosis and management of pheochromocytoma. Curr Probl Surg. 2014;51(4):151–87.

    Article  Google Scholar 

  • Karasek D, Frysak Z, Pacak K. Genetic testing for pheochromocytoma. Curr Hypertens Rep. 2010;12(6):456–64.

    Article  Google Scholar 

  • Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet. 2005;366(9486):665–75.

    Article  Google Scholar 

  • Lenders JW, Duh QY, Eisenhofer G, et al. Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(6):1915–42.

    Article  CAS  Google Scholar 

  • Neary NM, King KS, Pacak K. Drugs and pheochromocytom-don’t be fooled by every elevated metanephrine. N Engl J Med. 2011;364(23):2268–70.

    Article  CAS  Google Scholar 

  • Plouin PF, Amar L, Dekkers OM, et al. European Society of Endocrinology Clinical Practice Guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma. Eur J Endocrinol. 2016;174(5):G1–G10.

    Article  CAS  Google Scholar 

  • Ricketts CJ, Forman JR, Rattenberry E, et al. Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. Hum Mutat. 2010;31(1):41–51.

    Article  CAS  Google Scholar 

  • Sawka AM, Jaeschke R, Singh RJ, Young WF. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003;88(2):553–8.

    Article  CAS  Google Scholar 

  • Scholz T, Eisenhofer G, Pacak K, Dralle H, Lehnert H. Clinical review: current treatment of malignant pheochromocytoma. J Clin Endocrinol Metab. 2007;92(4):1217–25.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

    Eugene J. Park

  2. Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

    Masha J. Livhits

  3. Department of Surgery, University of California, Irvine, Orange, CA, USA

    Areg Grigorian

  4. Surgery and Medicine, Section of Endocrine Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA, USA

    Michael W. Yeh

Authors
  1. Eugene J. Park
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  2. Masha J. Livhits
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  3. Areg Grigorian
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  4. Michael W. Yeh
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Corresponding author

Correspondence to Eugene J. Park .

Editor information

Editors and Affiliations

  1. Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA, USA

    Christian de Virgilio

  2. Department of Surgery, Suite 1600, University of California, Ivine, Orange, CA, USA

    Areg Grigorian

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Park, E.J., Livhits, M.J., Grigorian, A., Yeh, M.W. (2020). Intermittent Episodes of Sweating, Palpitations, and Hypertension. In: de Virgilio, C., Grigorian, A. (eds) Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-05387-1_13

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  • DOI: https://doi.org/10.1007/978-3-030-05387-1_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-05386-4

  • Online ISBN: 978-3-030-05387-1

  • eBook Packages: MedicineMedicine (R0)

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