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Subarachnoid Hemorrhage pp 191–194Cite as

The Сerebrovascular Time Constant in Patients with Head Injury and Posttraumatic Cerebral Vasospasm

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Part of the book series: Acta Neurochirurgica Supplement ((NEUROCHIRURGICA,volume 127))

Abstract

The aim of the study was to assess the time constant of cerebral arterial bed in TBI patients with cerebral vasospasm (CVS) with and without intracranial hematomas (ICH).

We examined 84 patients with severe TBI (mean 35 ± 15 years, 53 men and 31 women). The first group included 41 patients without ICH and the second group included 43 patients with epidural (7) and subdural (36) hematomas.

Perfusion computed tomography (PCT) was performed in 1–12 days after TBI in the first group and in 2–8 days after craniotomy in the second group. Arteriovenous amplitude of regional cerebral blood volume oscillation was calculated as the difference of arterial and venous blood volume in the “region of interest.” Mean arterial pressure was measured and the flow rate of middle cerebral artery was recorded with Transcranial Doppler after PCT. Time constant was calculated by the formula modificated by M. Kasprowicz.

Results and Conclusion: The τ was shorter (p < 0.005) in both first and second group in comparison with normal values. The τ in the second group on ipsilateral side former hematoma with CVS was shorter than in the first group and in the second group on contralateral side former hematoma without CVS (р = 0.024).

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Conflict of Interest

We declare that we have no conflicts of interest.

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Authors and Affiliations

  1. Department of Neurosurgery, Privolzhsky Research Medical University, Nizhny Novgorod, Russia

    Anatoly Sheludyakov & Alex Trofimov

  2. Nizhny Novgorod State Technical University Named After R.E. Alexeev, Nizhny Novgorod, Russia

    Dmitry Martynov

  3. Department of Polytrauma, Regional Hospital Named After N.A. Semashko, Nizhny Novgorod, Russia

    Michael Yuryev, Artem Kopylov & Alex Trofimov

Authors
  1. Anatoly Sheludyakov
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  2. Dmitry Martynov
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  3. Michael Yuryev
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  4. Artem Kopylov
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  5. Alex Trofimov
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Editor information

Editors and Affiliations

  1. Department of Anethesiology, Loma Linda University Medical Center, Loma Linda, CA, USA

    Robert D. Martin

  2. Department of Neurosurgery, Loma Linda University Medical Center, Loma Linda, CA, USA

    Warren Boling

  3. Department of Neurosurgery, First Affiliated Hospital of Soochow University, Suzhou, China

    Gang Chen

  4. Department of Anesthesiology and Physiology, Loma Linda University Medical Center, Loma Linda, CA, USA

    John H. Zhang

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Sheludyakov, A., Martynov, D., Yuryev, M., Kopylov, A., Trofimov, A. (2020). The Сerebrovascular Time Constant in Patients with Head Injury and Posttraumatic Cerebral Vasospasm. In: Martin, R., Boling, W., Chen, G., Zhang, J. (eds) Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement, vol 127. Springer, Cham. https://doi.org/10.1007/978-3-030-04615-6_30

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  • DOI: https://doi.org/10.1007/978-3-030-04615-6_30

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-04614-9

  • Online ISBN: 978-3-030-04615-6

  • eBook Packages: MedicineMedicine (R0)

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