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Clinical Ophthalmic Oncology pp 295–308Cite as

Diagnostic Techniques: FNAB

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Abstract

Biopsy involves the removal of a tissue sample, laboratory analysis, and interpretation of the results. The usual objective of biopsy has been to establish or confirm a diagnosis. For example, intraocular biopsy is useful when clinical examination fails to distinguish a melanoma from a nevus or metastasis. Even when there is a confident clinical diagnosis, biopsy may be performed to determine the tumor subtype. A uveal tumor can be sampled by aspirational, incisional, or excisional biopsy techniques, depending on its size and location in the eye. Close collaboration with the cytopathologist is essential to ensure adequate sample size and handling. Aspiration biopsy is essentially contraindicated if retinoblastoma is a possibility. In this chapter, we review techniques, indications, complications, and the limitations of intraocular biopsies. Techniques for biopsy of conjunctival, eyelid, and orbital tumors are covered elsewhere in their respective volumes.

Other biopsy techniques such as incisional and excisional biopsy and diagnostic vitrectomy are discussed elsewhere.

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Author information

Authors and Affiliations

  1. Clemenceau Medical Center, Beirut, Lebanon

    Hassan A. Aziz

  2. Department of Ophthalmology, Buenos Aires University and Maimonides University, Buenos Aires, Argentina

    David Pelayes

  3. Department of Anatomic Pathology and Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Charles V. Biscotti

  4. Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Arun D. Singh

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  1. Hassan A. Aziz
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  2. David Pelayes
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  3. Charles V. Biscotti
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  4. Arun D. Singh
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Corresponding author

Correspondence to Hassan A. Aziz .

Editor information

Editors and Affiliations

  1. Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Arun D. Singh

  2. Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK

    Bertil E. Damato

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Aziz, H.A., Pelayes, D., Biscotti, C.V., Singh, A.D. (2019). Diagnostic Techniques: FNAB. In: Singh, A., Damato, B. (eds) Clinical Ophthalmic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-04489-3_23

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  • DOI: https://doi.org/10.1007/978-3-030-04489-3_23

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