Abstract
The threat caused by drug-resistant pathogens represents a great concern to several economic sectors. This issue has intensified the development of more efficient antimicrobial products that could be safe not only for medical, pharmaceutical, water disinfection and food applications but also for reduced environmental impact. Nanotechnology now emerges as a powerful tool for scientists and engineers to develop engineered nanomaterials with remarkable antimicrobial activity. The potential of engineered nanomaterials is now certain to benefit different areas, such as medicine, food, pharmaceutical, and agriculture, once higher antimicrobial effectiveness implies in reduced content of antimicrobial compounds, thereby reducing cytotoxicity effects as well as environmental impact to different forms of life. This chapter summarizes the most recent achievements on antimicrobial engineered nanomaterials intended for better medicine, cosmetics, environmental, and food applications with emphasis on (i) new silver-based hybrid nanomaterials, (ii) new bioinspired antimicrobial nanoparticles, (iii) new antimicrobial nanostructures derived from layered minerals, (iv) recent developments on antimicrobial polymer nanocomposites, and finally (v) some recent trends in nanotechnological antimicrobial products available at the European market. The remarkable importance of antimicrobial engineered nanomaterials emerges from the combination of different nanomaterials so that main advantages of each are built together into new, revolutionary systems capable of solving the pathogen infection issue.
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References
Aani SA, Gomez V, Wright CJ, Hilal N (2017) Fabrication of antibacterial mixed matrix nanocomposite membranes using hybrid nanostructure of silver coated multi-walled carbon nanotubes. Chem Eng J 326:721–736. https://doi.org/10.1016/j.cej.2017.06.029
Abreu AS, Oliveira M, Rodrigues De SA, Cerqueira MA, Vicente AA, Machado AV (2015) Antimicrobial nanostructured starch based films for packaging. Carbohydr Polym 129:127–134. https://doi.org/10.1016/j.carbpol.2015.04.021
Aider M (2010) Chitosan application for active bio-based films production and potential in the food industry. Review LWT Food Sci Technol 43(6):837–842. https://doi.org/10.1016/j.lwt.2010.01.021
Alsaleh NB, Brown JM (2018) Immune responses to engineered nanomaterials: current understanding and challenges. Curr Opin Toxicol 10:8–14. https://doi.org/10.1016/j.cotox.2017.11.011
Alzate P, Zalduendo PM, Gerschenson L, Flores SK (2016) Micro and nanoparticles of native and modified cassava starches as carriers of the antimicrobial potassium sorbate. Starch/Stärke 68:1038–1047. https://doi.org/10.1002/star.2016000981038
Ameeduzzafar, Imam SS, Bukhari SNA, Ahmad J, Ali A (2018) Formulation and optimization of levofloxacin loaded chitosan nanoparticle for ocular delivery: in-vitro characterization, ocular tolerance and antibacterial activity. Int J Biol Macromol 108:650–659. https://doi.org/10.1016/j.ijbiomac.2017.11.170
Arora D, Sharma N, Sharma V, Abrol V, Shankar R, Jaglan S (2016) An update on polysaccharide-based nanomaterials for antimicrobial applications. Appl Microbiol Biotechnol 100:2603–2615. https://doi.org/10.1007/s00253-016-7315-0
Balagna C, Irfan M, Perero S, Miola M, Maina G, Santella D, Simone A (2017) Characterization of antibacterial silver nanocluster/silica composite coating on high performance Kevlar® textile. Surf Coat Technol 321:438–447. https://doi.org/10.1016/j.surfcoat.2017.05.009
Barzegar H, Azizi MH, Barzegar M, Hamidi-Esfahani Z (2014) Effect of potassium sorbate on antimicrobial and physical properties of starch-clay nanocomposite films. Carbohydr Polym 110:26–31. https://doi.org/10.1016/j.carbpol.2014.03.092
Bilal M, Rasheed T, Muhammad H, Iqbal N, Hu H, Zhang X (2017) Silver nanoparticles: biosynthesis and antimicrobial potentialities. Int J Antimicrob Agents 49:137–152. https://doi.org/10.3923/ijp.2017.832.845
Bugatti V, Gorrasi G, Montanari F, Nocchetti M, Tammaro L, Vittoria V (2011) Modified layered double hydroxides in polycaprolactone as a tunable delivery system: In vitro release of antimicrobial benzoate derivatives. Appl Clay Sci 52:1–2. https://doi.org/10.1016/j.clay.2011.01.025
Carja G, Niiyama H, Ciobanu G, Aida T (2007) Towards new drugs formulations: Gentamicin-anionic clay as nanohybrids. Mater Sci Eng C 27:1129–1132. https://doi.org/10.1016/j.msec.2006.07.017
Chakraborti M, Jackson JK, Plackett D, Gilchrist SE, Burt HM (2012) The application of layered double hydroxide clay (LDH)-poly(lactide-co- glycolic acid) (PLGA) film composites for the controlled release of antibiotics. J Mater Sci Mater Med 23(7):1705–1713. https://doi.org/10.1007/s10856-012-4638-y
Chen C, Gunawan P, Lou XW, Xu R (2012) Silver nanoparticles deposited layered double hydroxide nanoporous coatings with excellent antimicrobial activities. Adv Funct Mater 22(4):780–787. https://doi.org/10.1002/adfm.201102333
Chernousova S, Epple M (2013) Silver as antibacterial agent: ion, nanoparticle, and metal. Angew Chem Int Ed 52:1636–1653. https://doi.org/10.1002/anie.201205923
Cohen E, Joseph T, Lapides I, Yariv S (2005) The adsorption of berberine by montmorillonite and thermo-XRD analysis of the organo-clay complex. Clay Miner 40(2):223–232. https://doi.org/10.1180/0009855054020168
Costa JR, Silva NC, Sarmento B, Pintado M (2015) Potential chitosan-coated alginate nanoparticles for ocular delivery of daptomycin. Eur J Clin Microbiol Infect Dis 34(6):1255–1262. https://doi.org/10.1007/s10096-015-2344-7
Costantino U, Bugatti V, Gorrasi G, Montanari F, Nocchetti M, Tammaro L, Vittoria V (2009) New polymeric composites based on poly(ε-caprolactone) and layered double hydroxides containing antimicrobial species. ACS Appl Mater Interfaces 1(3):668–677. https://doi.org/10.1021/am8001988
Da Rosa CG, Maciel MVOB, de Carvalho SB, de Melo APZ, Jummes B, da Silva T, Martelli SM, Villetti MA, Bertoldi FC, Barreto PLM (2015) Characterization and evaluation of physicochemical and antimicrobial properties of zein nanoparticles loaded with phenolics monoterpenes. Colloids Surf A Physicochem Eng Asp 481:337–344. https://doi.org/10.1016/j.colsurfa.2015.05.019
Das MR, Sarma RK, Saikia R, Kale VS, Shelke MV, Sengupta P (2011) Synthesis of silver nanoparticles in an aqueous suspension of graphene oxide sheets and its antimicrobial activity. Colloids Surf B Biointerfaces 83(1):16–22. https://doi.org/10.1016/j.colsurfb.2010.10.033
De Marchi JGB, Jornada DS, Silva FK, Freitas AL, Fuentefria AM, Pohlmann AR, Guterres SS (2017) Triclosan resistance reversion by encapsulation in chitosan-coated-nanocapsule containing α-bisabolol as core: development of wound dressing. Int J Nanomedicine 12:7855–7868. https://doi.org/10.2147/IJN.S143324
Djebbi MA, Elabed A, Bouaziz Z, Sadiki M, Elabed S, Namour P, Jaffrezic-Renault N, Amara ABH (2016a) Delivery system for berberine chloride based on the nanocarrier ZnAl-layered double hydroxide: physicochemical characterization, release behavior and evaluation of anti-bacterial potential. Int J Pharm 515:1–2. https://doi.org/10.1016/j.ijpharm.2016.09.089
Djebbi MA, Bouaziz Z, Elabed A, Sadiki M, Elabed S, Namour P, Jaffrezic-Renault N, Amara ABH (2016b) Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite. Int J Pharm 506:1–2. https://doi.org/10.1016/j.ijpharm.2016.04.048
Durán N, Durán M, de Jesus MB, Seabra AB, Fávaro WJ, Nakazato G (2016) Silver nanoparticles: a new view on mechanistic aspects on antimicrobial activity. Nanomedicine 12(3):789–799. https://doi.org/10.1016/j.nano.2015.11.016
Etewa SE, El-Maaty DAA, Hamza RS, Metwaly AS, Sarhan MH, Abdel-Rahman SA, Fathy GM, El-Shafey MA (2018) Assessment of spiramycin-loaded chitosan nanoparticles treatment on acute and chronic toxoplasmosis in mice. J Parasit Dis 42(1):102–113. https://doi.org/10.1007/s12639-017-0973-8
European Commission (2015) Definition – nanomaterials – environment – European Commission. online. European Commission available at: http://ec.europa.eu/environment/chemicals/nanotech/faq/definition_en.htm
Girase B, Depan D, Shah JS, Xu W, Misra RDK (2011) Silver-clay nanohybrid structure for effective and diffusion-controlled antimicrobial activity. Mater Sci Eng C 31(8):1759–1766. https://doi.org/10.1016/j.msec.2011.08.007
Gorrasi G, Bugatti V, Vittoria V (2012) Pectins filled with LDH-antimicrobial molecules: preparation, characterization and physical properties. Carbohydr Polym 89(1):132–137. https://doi.org/10.1016/j.carbpol.2012.02.061
Häffner SM, Nyström L, Nordström R, Xu ZP, Davoudi M, Schmidtchen S, Malmsten M (2017) Membrane interactions and antimicrobial effects of layered double hydroxide nanoparticles. Phys Chem Chem Phys 19(35):23832–23842. https://doi.org/10.1039/C7CP02701J
Hajipour ML, Fromm KM, Ashkarran AA, de Aberasturi DJ, de Larramendi IR, Rojo T, Serpoonshan V, Parak W, Mahmoundi M (2012) Antibacterial properties of nanoparticles. Trends Biotechnol 30(10). https://doi.org/10.1016/j.tibtech.2012.06.004
Heydari A, Alemzadeh I, Vossoughi M (2013) Functional properties of biodegradable corn starch nanocomposites for food packaging applications. Mater Des 50:954–961. https://doi.org/10.1016/j.matdes.2013.03.084
Hoseinzadeh E, Makhdoumi P, Taha P, Hossini H, Stelling J, Kamal MA, Ashraf GM (2017) A review on nano-antimicrobials: metal nanoparticles, methods and mechanisms. Curr Drug Metab 18(2):120–128. https://doi.org/10.2174/1389200217666161201111146
Iannuccelli V, Maretti E, Montorsi M, Rustichelli C, Sacchetti F, Leo E (2015) Gastroretentive montmorillonite-tetracycline nanoclay for the treatment of Helicobacter pylori infection. Int J Pharm 493:1–2. https://doi.org/10.1016/j.ijpharm.2015.06.049
Incoronato AL, Buonocore GG, Conte A, Lavorgna M, Del Nobile MA (2010) Active systems based on silver-montmorillonite nanoparticles embedded into bio-based polymer matrices for packaging applications. J Food Prot 73(12):2256. https://doi.org/10.4315/0362-028X-73.12.2256
Ismail NS, Gopinath SCB (2017) Enhanced antibacterial effect by antibiotic loaded starch nanoparticle. J Assoc Arab Uni Basic Appl Sci 24:136–140. https://doi.org/10.1016/j.jaubas.2016.10.005
Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H (2011) Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnol Adv 29(3):322–337. https://doi.org/10.1016/j.biotechadv.2011.01.005
Jayrajsinh S, Shankar G, Agrawal YK, Bakre L (2017) Montmorillonite nanoclay as a multifaceted drug-delivery carrier: a review. J Drug Deliv Sci Technol 39:200–209. https://doi.org/10.1016/j.jddst.2017.03.023
Jung J, Kasi G, Seo J (2018) Development of functional antimicrobial papers using chitosan/starch-silver nanoparticles. Int J Biol Macromol 112:530–553. https://doi.org/10.1016/j.ijbiomac.2018.01.155
Kanmani P, Rhim JW (2014) Physical, mechanical and antimicrobial properties of gelatin based active nanocomposite films containing AgNPs and nanoclay. Food Hydrocoll 35:644–652. https://doi.org/10.1016/j.foodhyd.2013.08.011
Kevadiya BD, Rajkumar S, Bajaj HC, Chettiar SS, Gosai K, Brahmbhatt H, Bhatt AS, Barvaliya YK, Dave GS, Kothari RK (2014) Biodegradable gelatin-ciprofloxacin-montmorillonite composite hydrogels for controlled drug release and wound dressing application. Colloids Surf B Biointerfaces 122:175–183. https://doi.org/10.1016/j.colsurfb.2014.06.051
Kim JP, Kim JH, Kim J, Lee SN, Park H (2016) A nanofilter composed of carbon nanotube-silver composites for virus removal and antibacterial activity improvement. J Environ Sci 42:275–283. https://doi.org/10.1016/j.jes.2014.11.017
Lavorgna M, Piscitelli F, Mangiacapra P, Buonocore GG (2010) Study of the combined effect of both clay and glycerol plasticizer on the properties of chitosan films. Carbohydr Polym 82(2):291–298. https://doi.org/10.1016/j.carbpol.2010.04.054
Ma Z, Garrido-Maestu A, Jeong KC (2017) Application, mode of action, and in vivo activity of chitosan and its micro and nanoparticles as antimicrobial agents: a review. Carbohydr Polym 176:257–265. https://doi.org/10.1016/j.carbpol.2017.08.08
Mahor A, Prajapati SK, Verma A, Gupta R, Iyer AK, Kesharwani P (2016) Moxifloxacin loaded gelatin nanoparticles for ocular delivery: formulation and in-vitro, in-vivo evaluation. J Colloid Interface Sci 483:132–138. https://doi.org/10.1016/j.jcis.2016.08.018
Martins JT, Bourbon AI, Pinheiro AC, Souza BWS, Cerqueira MA, Vicente AA (2013) Biocomposite films based on κ-carrageenan/locust bean gum blends and clays: physical and antimicrobial properties. Food Bioprocess Technol 6(8):2081–2092. https://doi.org/10.1007/s11947-012-0851-4
Melo NFCB, Soares BLM, Diniz KM, Leal CF, Canto D, Flores MAP, Tavares-Filho JHC, Galembeck A, Stamford TLM, Stamford-Arnaud TM, Stamford TCM (2018) Effects of fungal chitosan nanoparticles as eco-friendly edible coatings on the quality of postharvest table grapes. Postharvest Biol Technol 139:56–66. https://doi.org/10.1016/j.postharvbio.2018.01.014
Motshekga SC, Ray SS, Maity A (2018) Synthesis and characterization of alginate beads encapsulated zinc oxide nanoparticles for bacteria disinfection in water. J Colloid Interface Sci 512:686–692. https://doi.org/10.1016/j.jcis.2017.10.098
Noronha VT, Paula JÁ, Durán G, Galembeck A, Cogo-Müller K, Franz-Montan M, Durán N (2017) Silver nanoparticles in dentistry. Dent Mater 33:1110–1116. https://doi.org/10.1016/j.dental.2017.07.002
Pan K, Chen H, Davidson PM, Zhong Q (2014) Thymol nanoencapsulated by sodium caseinate: physical and antilisterial properties. J Agric Food Chem 62:1649–1657. https://doi.org/10.1021/jf4055402
Panwar K, Jassal M, Agrawal AK (2018) Readily dispersible antimicrobial Ag – SiO2 Janus particles and their application on cellulosic fabric. Carbohydr Polym 187(2018):43–50. https://doi.org/10.1016/j.carbpol.2018.01.076
Park M, Lee CII, Seo YJ, Woo SR, Shin D, Choi J (2010) Hybridization of the natural antibiotic, cinnamic acid, with layered double hydroxides (LDH) as green pesticide. Environ Sci Pollut Res 17(1):203–209. https://doi.org/10.1007/s11356-009-0235-0
Park S, Ko Y, Jung H, Lee C, Woo K, Ko G (2018) Disinfection of waterborne viruses using silver nanoparticle-decorated silica hybrid composites in water environments. Sci Total Environ 625:477–485. https://doi.org/10.1016/j.scitotenv.2017.12.318
Parolo ME, Avena MJ, Pettinari G, Zajonkovsky I, Valles JM, Baschini MT (2010) Antimicrobial properties of tetracycline and minocycline-montmorillonites. Appl Clay Sci 49(3):194. https://doi.org/10.1016/j.clay.2010.05.005
Pender DS, Vangala LM, Badwaik VD, Willis CB, Aguilar ZP, Sangoi TN, Paripelly R, Dakshinamurt R (2013) Bactericidal activity of starch-encapsulated gold nanoparticles. Front Biosci 18:993–1002
Perinelli DR, Fagioli L, Campana R, Lam JKW, Baffone W, Palmieri GF, Casettari L, Bonacucina G (2018) Chitosan-based nanosystems and their exploited antimicrobial activity. Eur J Pharm Sci 117:8–20. https://doi.org/10.1016/j.ejps.2018.01.046
Popova M, Lazarova H, Trusheva B, Popova M, Bankova V, Mihály J, Najdenski H, Tsvetkova I, Szegedi A (2018) Nanostructured silver silica materials as potential propolis carriers. Microporous Mesoporous Mater 263:28–33. https://doi.org/10.1016/j.micromeso.2017.11.043
Praphakar RA, Munusamy MA, Alarfaj AA, Suresh Kumar S, Rajan M (2017) Zn2+ cross-linked sodium alginate-g-allylamine-mannose polymeric nanocarrier of rifampicin for macrophage targeting tuberculosis nanotherapy. New J Chem 41(19):11324–11334. https://doi.org/10.1039/c7nj01808h
Priebe M, Widmer J, Löwa NS, Abram S-L, Mottas I, Woischnig A-K, Brunetto PS, Khanna N, Bourquin C, Fromm KM (2017) Antimicrobial silver-filled silica nanorattles with low immunotoxicity in dendritic cells. Nanomedicine 13:11–22. https://doi.org/10.1016/j.nano.2016.08.002
Qiu C, Chang R, Yang J, Ge S, Xiong L, Zhao M, Li M, Sun Q (2017) Preparation and characterization of essential oil-loaded starch nanoparticles formed by short glucan chains. Food Chem 221:1426–1433. https://doi.org/10.1016/j.foodchem.2016.11.009
Raghunath A, Perumal E (2017) Metal oxide nanoparticles as antimicrobial agents: a promise for the future. Int J Antimicrob Agents 49:137–152. https://doi.org/10.1016/j.ijantimicag.2016.11.011
Rajendran NK, Kumar SSD, Houreld NN, Abrahamse H (2018) A review on nanoparticle based treatment for wound healing. J Drug Deliv Sci Technol 44:421–430. https://doi.org/10.1016/j.jddst.2018.01.009
Rapacz-Kmita A, Bućko MM, Stodolak-Zych E, Mikołajczyk M, Dudek P, Trybus M (2017) Characterisation, in vitro release study, and antibacterial activity of montmorillonite-gentamicin complex material. Mater Sci Eng C 70:471–478. https://doi.org/10.1016/j.msec.2016.09.031
Rhim JW, Hong SI, Park HM, Ng PKW (2006) Preparation and characterization of chitosan-based nanocomposite films with antimicrobial activity. J Agric Food Chem 54(16):5814–5822. https://doi.org/10.1021/jf060658h
Rytwo G, Varman H, Bluvshtein N, König TN, Mendelovits A, Sandler A (2011) Adsorption of berberine on commercial minerals. Appl Clay Sci 51(1–2):43–50. https://doi.org/10.1016/j.clay.2010.10.031
Ryu SJ, Jung H, Oh JM, Lee JK, Choy JH (2010) Layered double hydroxide as novel antibacterial drug delivery system. J Phys Chem Solids 71(4):685–688. https://doi.org/10.1016/j.jpcs.2009.12.066
Salam MA, Obaid AY, El-Shishtawy RM, Mohamed SA (2017) Synthesis of nanocomposites of polypyrrole/carbon nanotubes/silver nano particles and their application in water disinfection. RSC Adv 7:16878–16884. https://doi.org/10.1039/c7ra01033h
Sharma C, Dhiman R, Rokana N, Panwar H (2017) Nanotechnology: An updated resource for food packaging. Front Microbiol 8:1735. https://doi.org/10.3389/fmicb.2017.01735
Shevlin D, O’Brien N, Cummins E (2018) Silver engineered nanoparticles in freshwater systems– likely fate and behaviour through natural attenuation processes. Sci Total Environ 621:1033–1046. https://doi.org/10.1016/j.scitotenv.2017.10.123
Suganya P, Vaseeharan B, Vijayakumar S, Balan B, Govindarajan M, Alharbi NS, Kadaikunnan S, Khaled JM, Benelli G (2017) Biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the Zika virus vector Aedes aegypti. J Photochem Photobiol B Biol 173:404–411. https://doi.org/10.1016/j.jphotobiol.2017.06.004
Sun Z, Gu L, Zheng J, Zhang J, Wang L, Xu F, Lin C (2016) A controlled release strategy of antifouling agent in coating based on intercalated layered double hydroxides. Mater Lett 172:105–108. https://doi.org/10.1016/j.matlet.2016.02.151
Trikeriotis M, Ghanotakis DF (2007) Intercalation of hydrophilic and hydrophobic antibiotics in layered double hydroxides. Int J Pharm 332(1–2):176–184. https://doi.org/10.1016/j.ijpharm.2006.09.031
Tunç S, Duman O (2011) Preparation of active antimicrobial methyl cellulose/carvacrol/montmorillonite nanocomposite films and investigation of carvacrol release. LWT – Food Sci Technol 44(2):465–472. https://doi.org/10.1016/j.lwt.2010.08.018
Wang Y, Zhang D (2012) Synthesis, characterization, and controlled release antibacterial behavior of antibiotic intercalated Mg-Al layered double hydroxides. Mater Res Bull 47(11):3185–3194. https://doi.org/10.1016/j.materresbull.2012.08.029
Wei L, Lu J, Xu H, Patel A, Chen Z-S, Chen G (2015) Silver nanoparticles: synthesis, properties, and therapeutic applications. Drug Discov Today 20(5). https://doi.org/10.1016/j.drudis.2014.11.014
Woodruff MA, Hutmacher DW (2010) The return of a forgotten polymer – polycaprolactone in the 21st century. Prog Polym Sci 35(10):1217–1256. https://doi.org/10.1016/j.progpolymsci.2010.04.002
Wu TS, Wang KX, Li GD, Sun SY, Sun J, Chen JS (2010) Montmorillonite-supported Ag/TiO2 nanoparticles: an efficient visible-light bacteria photodegradation material. ACS Appl Mater Interfaces 2(2):544–550. https://doi.org/10.1021/am900743d
Wu T, Xie A, Tan S, Cai X (2011) Antimicrobial effects of quaternary phosphonium salt intercalated clay minerals on Escherichia coli and Staphylococci aureus. Colloids Surf B Biointerfaces 86(1):232–236. https://doi.org/10.1016/j.colsurfb.2011.04.009
Xia L, Xu M, Cheng G, Yang L, Guo Y, Li D, Fang D, Zhang Q, Liu H (2018) Facile construction of Ag nanoparticles encapsulated into carbon nanotubes with robust antibacterial activity. Carbon 130:775–781. https://doi.org/10.1016/j.carbon.2018.01.073
Yang M, Lianghua G, Bin Y, Li W, Sun Z, Zheng J, Zhang J, Hou J (2017) Antifouling composites with self-adaptive controlled release based on an active compound intercalated into layered double hydroxides. Appl Surf Sci 426:185–193. https://doi.org/10.1016/j.apsusc.2017.07.207
Youssef HF, Abdel-Aziz MS, Fouda FK (2017) Evaluation of antimicrobial activity of different silver-exchanged nano and micronized zeolites prepared by microwave technique. J Porous Mater 24(4):947–957. https://doi.org/10.1007/s10934-016-0334-5
Zimet P, Mombrú AW, Faccio R, Brugnini G, Miraballes I, Rufo C, Pardo H (2018) Optimization and characterization of nisin-loaded alginate-chitosan nanoparticles with antimicrobial activity in lean beef. LWT Food Sci Technol 91:107–116. https://doi.org/10.1016/j.lwt.2018.01.015
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Authors thank Embrapa, DEMa/UFSCar, FAPESP, CNPq, FAPESP (Proc. No. 2015/00094-0; Proc. No. 2017/22017-3), MCTI/SISNANO, and REDEAGRONANO for the financial support.
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Bernardo, M.P., Moreira, F.K.V., Mattoso, L.H.C., Raja, S. (2019). Innovations in Antimicrobial Engineered Nanomaterials. In: Naushad, M., Rajendran, S., Gracia, F. (eds) Advanced Nanostructured Materials for Environmental Remediation. Environmental Chemistry for a Sustainable World, vol 25. Springer, Cham. https://doi.org/10.1007/978-3-030-04477-0_10
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