Skip to main content

Atrial Fibrillation: Aggressive Treatment in the Postoperative Cardiothoracic Surgery Patient

  • Chapter
  • First Online:
Difficult Decisions in Cardiothoracic Critical Care Surgery

Abstract

Atrial fibrillation (AF) occurs in approximately 35% of patients following cardiac surgery and 10–30% of patients following thoracic surgery, depending on the patient’s underlying risk factors for AF and the type of surgery. Postoperative atrial fibrillation (POAF) is associated with numerous detrimental sequelae, including an increased risk of stroke, cardiac arrest, respiratory and renal failure, and all-cause mortality. Pre- and postoperative prophylaxis and treatment of POAF are centered around the use of beta blockers, amiodarone, and/or nondihydropyridine calcium channel blockers, with direct current (DC) cardioversion used as necessary in high-risk patients who develop POAF. Numerous other medications and modalities, such as biatrial pacing, have been used for POAF prophylaxis and treatment with limited success.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Frendl G, Sodickson AC, Chung MK, Waldo AL, Gersh BJ, Tisdale JE, et al. 2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. J Thorac Cardiovasc Surg. 2014;148(3):e153–93.

    Article  Google Scholar 

  2. Philip I, Berroeta C, Leblanc I. Perioperative challenges of atrial fibrillation. Curr Opin Anaesthesiol. 2014;27(3):344–52.

    Article  Google Scholar 

  3. Gillinov AM, Bagiella E, Moskowitz AJ, Raiten JM, Groh MA, Bowdish ME, et al. Rate control versus rhythm control for atrial fibrillation after cardiac surgery. N Engl J Med. 2016;374(20):1911–21.

    Article  CAS  Google Scholar 

  4. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64(21):e1–76.

    Article  Google Scholar 

  5. Onk OA, Erkut B. Is the preoperative administration of amiodarone or metoprolol more effective in reducing atrial fibrillation: after coronary bypass surgery? Medicine (Baltimore). 2015;94(41):e1576.

    Article  CAS  Google Scholar 

  6. Zakkar M, Ascione R, James AF, Angelini GD, Suleiman MS. Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery. Pharmacol Ther. 2015;154:13–20.

    Article  CAS  Google Scholar 

  7. Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37(38):2893–962.

    Article  Google Scholar 

  8. Shen J, Lall S, Zheng V, Buckley P, Damiano RJ Jr, Schuessler RB. The persistent problem of new-onset postoperative atrial fibrillation: a single-institution experience over two decades. J Thorac Cardiovasc Surg. 2011;141(2):559–70.

    Article  Google Scholar 

  9. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. 2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2011;123(10):e269–367.

    Article  Google Scholar 

  10. Arsenault KA, Yusuf AM, Crystal E, Healey JS, Morillo CA, Nair GM, et al. Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery. Cochrane Database Syst Rev. 2013;1:CD003611.

    Google Scholar 

  11. Macle L, Cairns J, Leblanc K, Tsang T, Skanes A, Cox JL, et al. 2016 focused update of the Canadian cardiovascular society guidelines for the Management of Atrial Fibrillation. Can J Cardiol. 2016;32(10):1170–85.

    Article  Google Scholar 

  12. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg. 2012;143(1):4–34.

    Article  Google Scholar 

  13. Brinkman W, Herbert MA, O'Brien S, Filardo G, Prince S, Dewey T, et al. Preoperative beta-blocker use in coronary artery bypass grafting surgery: national database analysis. JAMA Intern Med. 2014;174(8):1320–7.

    Article  Google Scholar 

  14. Sezai A, Osaka S, Yaoita H, Ishii Y, Arimoto M, Hata H, et al. Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction: prevention of atrial fibrillation after cardiac surgery with landiolol hydrochloride for left ventricular dysfunction (PLATON) trial. J Thorac Cardiovasc Surg. 2015;150(4):957–64.

    Article  CAS  Google Scholar 

  15. Calkins H, Kuck KH, Cappato R, Brugada J, Camm AJ, Chen SA, et al. 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Europace. 2012;14(4):528–606.

    Article  Google Scholar 

  16. Lancaster TS, Schill MR, Greenberg JW, Moon MR, Schuessler RB, Damiano RJ Jr, et al. Potassium and magnesium supplementation do not protect against atrial fibrillation after cardiac operation: a time-matched analysis. Ann Thorac Surg. 2016;102(4):1181–8.

    Article  Google Scholar 

  17. Zheng Z, Jayaram R, Jiang L, Emberson J, Zhao Y, Li Q, et al. Perioperative Rosuvastatin in cardiac surgery. N Engl J Med. 2016;374(18):1744–53.

    Article  CAS  Google Scholar 

  18. Bhatt HV, Fischer GW. Atrial fibrillation: pathophysiology and therapeutic options. J Cardiothorac Vasc Anesth. 2015;29(5):1333–40.

    Article  Google Scholar 

  19. Mitchell LB, Committee CCSAFG. Canadian cardiovascular society atrial fibrillation guidelines 2010: prevention and treatment of atrial fibrillation following cardiac surgery. Can J Cardiol. 2011;27(1):91–7.

    Article  Google Scholar 

  20. Kowey PR, Dorian P, Mitchell LB, Pratt CM, Roy D, Schwartz PJ, et al. Vernakalant hydrochloride for the rapid conversion of atrial fibrillation after cardiac surgery: a randomized, double-blind, placebo-controlled trial. Circ Arrhythm Electrophysiol. 2009;2(6):652–9.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Spencer J. Melby MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Greenberg, J.W., Damiano, R.J., Melby, S.J. (2019). Atrial Fibrillation: Aggressive Treatment in the Postoperative Cardiothoracic Surgery Patient. In: Lonchyna, V. (eds) Difficult Decisions in Cardiothoracic Critical Care Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-04146-5_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-04146-5_16

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-04145-8

  • Online ISBN: 978-3-030-04146-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics