Phenolic Acids and Their Health-Promoting Activity

  • Sana Khatri
  • Additiya Paramanya
  • Ahmad AliEmail author


Plants are the primary sources for most of the food items for all organisms. Human beings have also used plants for purposes other than food, for example, for making tools and houses as well as medicine. Most of the civilizations have a rich history of traditional medicine based on plant extracts or preparations. In last few centuries, the active compounds from plants have been isolated and characterized. These active compounds belong to class of molecules called as secondary metabolites which are further divided into several subclasses: alkaloids, polyphenols, flavonoids, and terpenes. Polyphenols are a large group of secondary metabolites in plants. They are widely distributed among the plant species and are found in vegetables, fruits, and beans for tea and coffee. The common examples of polyphenols are flavonoids, phenolic acids, and lignans. There are many biological and pharmacological activities attributed to the phenolic acids. They have antioxidant, anti-inflammatory, and cytoprotective properties. With the emergence of diabetes as major metabolic disorder, there has been a search for natural compounds. In last two decades, there are many reports which have suggested the role of phenolic acids in the prevention of glycation-mediated secondary complications of diabetes. This chapter deals with the recent advances in the field of phenolic acids and their application in the treatment of disorders like diabetes and neurodegeneration.


Antioxidants Antiglycation Flavonoids Phenolic acids 



Advanced glycation end product


Proline-rich proteins


Reactive nitrogen species


Reactive oxygen species


Soil organic matter


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Authors and Affiliations

  1. 1.Department of Life SciencesUniversity of MumbaiMumbaiIndia

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