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Atlas of Clinical Neurology pp 597–667Cite as

Infectious Diseases of the Nervous System

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Abstract

Infectious diseases of the nervous system include bacterial, viral, fungal, spirochetal, and parasitic infections. Although the central nervous system (CNS) is protected from bacterial invasion by the intact blood-brain barrier, bacterial invasion is enhanced by the special surface properties of bacteria as well as host immune deficiencies. Similar to any type of infection of the nervous system, bacteria may involve any of the nervous system compartments: the epidural space (epidural abscess), the dura (pachymeningitis), the subdural space (subdural empyema), the leptomeninges and the subarachnoid space containing cerebrospinal fluid (meningitis or leptomeningitis), and the brain parenchyma (brain abscess). This chapter presents the clinical manifestations, pathogenesis, pathology, etiology, epidemiology, diagnosis, differential diagnosis, and treatment of these syndromes.

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Authors and Affiliations

  1. Departments of Neurology, Microbiology/Immunology, and Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA

    Burk Jubelt

  2. Department of Neurology, SUNY Upstate Medical University, Syracuse, NY, USA

    Laura E. Simionescu

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  1. University of Texas Southwestern Medical Center, Dallas, TX, USA

    Roger N. Rosenberg

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Jubelt, B., Simionescu, L.E. (2019). Infectious Diseases of the Nervous System. In: Rosenberg, R. (eds) Atlas of Clinical Neurology. Springer, Cham. https://doi.org/10.1007/978-3-030-03283-8_12

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