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Immunotherapy pp 131–149Cite as

Immune-Related Adverse Events: Pneumonitis

Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 995)

Abstract

Checkpoint inhibitors are part of the family of immunotherapies and are increasingly being used in a wide variety of cancers. Immune-related adverse events pose a major challenge in the treatment of cancer patients. Pneumonitis is a rare immune-related adverse event that presents in distinct patterns. The goal of this chapter is to instruct readers on the incidence and clinical manifestations of pneumonitis and to offer guidance in the evaluation and treatment of patients with pneumonitis.

Keywords

  • Checkpoint inhibitors
  • Immune-related adverse event
  • Pneumonitis
  • Thoracic imaging
  • Organizing pneumonia
  • Nonspecific interstitial pneumonia
  • Hypersensitivity pneumonitis
  • Diffuse alveolar damage

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Fig. 6.1
Fig. 6.2
Fig. 6.3

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Authors and Affiliations

  1. Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Akash Jain, Vickie R. Shannon & Ajay Sheshadri

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  1. Akash Jain
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  2. Vickie R. Shannon
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  3. Ajay Sheshadri
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Correspondence to Ajay Sheshadri .

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Editors and Affiliations

  1. MD Anderson Cancer Center, University of Texas, Houston, TX, USA

    Aung Naing

  2. Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, USA

    Dr. Joud Hajjar

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Jain, A., Shannon, V.R., Sheshadri, A. (2018). Immune-Related Adverse Events: Pneumonitis. In: Naing, A., Hajjar, J. (eds) Immunotherapy. Advances in Experimental Medicine and Biology, vol 995. Springer, Cham. https://doi.org/10.1007/978-3-030-02505-2_6

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