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Power of Self-Touch: Its Neural Mechanism as a Coping Strategy

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Emotional Engineering, Vol.7

Abstract

Self-touch is an act of coping with harmful or stressful situations based on suppression of somatosensory perception, somatosensory cortex activity, and sympathetic activity; however, the detailed neural mechanism remains unknown. Several studies have shown that the descending pain modulatory system (DPMS) plays critical roles in painful situations and that intrinsic functional connectivity in the DPMS is observed in even non-painful situations. Therefore, we hypothesized that the neural system consisting of the anterior cingulate cortex, amygdala, and rostral ventromedial medulla (RVM) would play a basic role in self-touch. We thus investigated the interactive effects of these regions in a pain-free self-touch situation. Functional magnetic resonance imaging was used to investigate brain activity induced by mere self-touch (rubbing the left hand with the right), and the physio-physiological interaction analysis was performed to investigate the modulatory effects of brain activity. Physio-physiological interaction analysis showed that the rostral anterior cingulate cortex modulated neural activity in the RVM and left cerebellum (CB) via the right amygdala, and the modulation linearly suppressed the RVM and left CB activity. Furthermore, the left CB activity was positively correlated with the right primary somatosensory cortex activity. Moreover, our study showed that coherent activity in the bilateral secondary somatosensory cortex modulated the activity of the left temporoparietal junction and RVM, and the RVM was suppressed in a linear manner. These results suggest that self-touch is a kind of passive avoidance automatically realized in the human brain to protect the self.

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References

  1. Hertenstein MJ, Verkamp JM, Kerestes AM et al (2006) The communicative functions of touch in humans, nonhuman primates, and rats: a review and synthesis of the empirical research. Genet Soc Gen Psychol Monogr 132:5–94

    Article  Google Scholar 

  2. Sharp H, Pickles A, Meaney M et al (2012) Frequency of infant stroking reported by mothers moderates the effect of prenatal depression on infant behavioural and physiological outcomes. PLoS ONE 7:e45446

    Article  Google Scholar 

  3. Maitre NL, Key AP, Chorna OD et al (2017) The dual nature of early-life experience on somatosensory processing in the human infant brain. Curr Biol 27:1048–1054

    Article  Google Scholar 

  4. Feldman R, Granat A, Pariente C et al (2009) Maternal depression andanxiety across the postpartum year and infant social engagement, fear regulation, and stress reactivity. J Am Acad Child Adolesc Psychiatry 48:919–927

    Article  Google Scholar 

  5. Maitre NL, Key AP, Chorna OD et al (2017) The dual nature of early-life experience on somatosensory processing in the human infant brain. Curr Biol 27:1048–1054

    Article  Google Scholar 

  6. Moore ER, Bergman N, Anderson GC et al (2016) Early skin-to-skin contact for mothers and their healthy newborn infants. Cochrane Database Syst Rev 5:CD003519

    Google Scholar 

  7. Premo JE, Kiel EJ (2014) The effect of toddler emotion regulation on maternal emotion socialization: moderation by toddler gender. Emotion 14:782–793

    Article  Google Scholar 

  8. Cameron JL (2001) Critical periods for social attachment: deprivation and neural systems in rhesus monkeys. Soc Res Child Development Abstr 2–054

    Google Scholar 

  9. Sabatini MJ, Ebert P, Lewis DA et al (2007) Amygdala gene expression correlates of social behavior in monkeys experiencing maternal separation. J Neurosci 27:3295–3304

    Article  Google Scholar 

  10. Knudsen EI, Heckman JJ, Judy L et al (2016) Economic, neurobiological, and behavioral perspectives on building America’s future workforce. Proc Natl Acad Sci USA 103:10155–10162

    Article  Google Scholar 

  11. Field T (2001) Touch. MIT Press, Cambridge, MA

    Google Scholar 

  12. Herrera E, Reissland N, Shepherd J (2004) Maternal touch and maternal child-directed speech: effects of depressed mood in the postnatal period. J Affect Disord 81:29–39

    Article  Google Scholar 

  13. Ekman P, Friesen WV (1969) Nonverbal leakage and clues to deception. Psychiatry 32:88–102

    Article  Google Scholar 

  14. Ekman P, Friesen WV (1974) Nonverbal behavior and psychopathology. In: Friedman RJ, Kats MM (ed) The psychology of depression: contemporary theory and research. Winston & Sons, Washington DC

    Google Scholar 

  15. Waxer PH (1977) Nonverbal cues for anxiety: an examination of emotional leakage. J Abnorm Psych 86:306–314

    Article  Google Scholar 

  16. Eysenck SBG, Eysenck HJ, Barrett P (1985) A revised version of the psychoticism scale. Person Individ Diff 6:21–29

    Article  Google Scholar 

  17. Harrigan JA (1985) Self-touching as an indicator of underlying affect and language processes. Soc Sci Med 20:1161–1168

    Article  Google Scholar 

  18. Kikuchi Y, Shirato M, Machida A et al (2018) The neural basis of self-touch in a pain-free situation. Neuropsychiatry 7:640–652

    Google Scholar 

  19. Friston KJ, Buechel C, Fink GR et al (1997) Psychophysiological and modulatory interactions in neuroimaging. Neuroimage 6:218–229

    Article  Google Scholar 

  20. Di X, Biswal BB (2013) Modulatory interactions of resting-state brain functional connectivity. PLoS ONE 8:e71163

    Article  Google Scholar 

  21. Zubieta JK, Ketter TA, Bueller JA et al (2003) Regulation of human affective responses by anterior cingulate and limbic mu-opioid neurotransmission. Arch Gen Psychiatry 60:1145–1153

    Article  Google Scholar 

  22. Wager TD, Atlas LY (2015) The neuroscience of placebo effects: connecting context, learning and health. Nat Rev Neurosci 16:403–418

    Article  Google Scholar 

  23. Fields H (2004) State-dependent opioid control of pain. Nat Rev Neurosci 5:565–575

    Article  Google Scholar 

  24. Petrovic P (2005) Opioid and placebo analgesia share the same network. Semin Pain Med 3:31–36

    Article  Google Scholar 

  25. Vogt BA, Wiley RG, Jensen EL (1995) Localization of Mu and delta opioid receptors to anterior cingulate afferents and projection neurons and input/output model of Mu regulation. Exp Neurol 135:83–92

    Article  Google Scholar 

  26. Jones AK, Qi LY, Fujirawa T et al (1991) In vivo distribution of opioid receptors in man in relation to the cortical projections of the medial and lateral pain systems measured with positron emission tomography. Neurosci Lett 126:25–28

    Article  Google Scholar 

  27. Willoch F, Schindler F, Wester HJ et al (2004) Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study. Pain 108:213–220

    Article  Google Scholar 

  28. Hopkins E, Spinella M, Pavlovic ZW et al (1998) Alterations in swim stress-induced analgesia and hypothermia following serotonergic or NMDA antagonists in the rostral ventromedial medulla of rats. Physiol Behav 64:219–225

    Article  Google Scholar 

  29. Fields HL, Malick A, Burstein R (1995) Dorsal horn projection targets of ON and OFF cells in the rostral ventromedial medulla. J Neurophysiol 74:1742–1759

    Article  Google Scholar 

  30. Heinricher MM, Morgan MM, Fields HL (1992) Direct and indirect actions of morphine on medullary neurons that modulate nociception. Neuroscience 48:533–543

    Article  Google Scholar 

  31. Dunckley P, Wise RG, Fairhurst M et al (2005) A comparison of visceral and somatic pain processing in the human brainstem using functional magnetic resonance imaging. J Neurosci 25:7333–7341

    Article  Google Scholar 

  32. Gwilym SE, Keltner JR, Warnaby CE et al (2009) Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis. Arthritis Rheum 61:1226–1234

    Article  Google Scholar 

  33. Kong J, Tu PC, Zyloney C et al (2010) Intrinsic functional connectivity of the periaqueductal gray, a resting fMRI study. Behav Brain Res 211:215–219

    Article  Google Scholar 

  34. Gowen MF, Ogburn SW, Suzuki T et al (2012) Collateralization of projections from the rostral ventrolateral medulla to the rostral and caudal thoracic spinal cord in felines. Exp Brain Res 220:121–123

    Article  Google Scholar 

  35. Cox BF, Brody MJ (1989) Subregions of rostral ventral medulla control arterial pressure and regional hemodynamics. Am J Physiol 257:R635–640

    Google Scholar 

  36. Babic T, Ciriello J (2004) Medullary and spinal cord projections from cardiovascular responsive sites in the rostral ventromedial medulla. J Comp Neurol 469:391–412

    Article  Google Scholar 

  37. Blakemore SJ, Wolpert DM, Frith CD (1998) Central cancellation of self-produced tickle sensation. Nat Neurosci 1:635–640

    Article  Google Scholar 

  38. Blakemore SJ, Wolpert DM, Frith CD (1999) The cerebellum contributes to somatosensory cortical activity during self-produced tactile stimulation. Neuroimage 10:448–459

    Article  Google Scholar 

  39. McDonald AJ (1998) Cortical pathways to the mammalian amygdala. Prog Neurobiol 55:257–332

    Article  Google Scholar 

  40. Costafreda SG, Brammer MJ, David AS et al (2008) Predictors of amygdala activation during the processing of emotional stimuli: a meta-analysis of 385 PET and fMRI studies. Brain Res Rev 58:57–70

    Article  Google Scholar 

  41. Harrison NA, Gray MA, Gianaros PJ et al (2010) The embodiment of emotional feelings in the brain. J Neurosci 30:12878–12884

    Article  Google Scholar 

  42. Critchley HD (2009) Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants. Int J Psychophysiol 73:88–94

    Article  Google Scholar 

  43. Critchley HD, Mathias CJ, Dolan RJ (2001) Neural activity in the human brain relating to uncertainty and arousal during anticipation. Neuron 29:537–545

    Article  Google Scholar 

  44. Medford N, Critchley HD (2010) Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response. Brain Struct Funct 214:535–549

    Article  Google Scholar 

  45. Anil KS, Suzuki K, Critchley H (2011) An interoceptive predictive coding model of conscious presence. Front Psychol 2:395

    Google Scholar 

  46. Barbas H, Saha S, Rempel-Clower N et al (2003) Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression. BMC Neurosci 4:25

    Article  Google Scholar 

  47. Barrett LF, Bar M (2009) See it with feeling: affective predictions during object perception. Philos Trans R Soc Lond B Biol Sci 364:1325–1334

    Article  Google Scholar 

  48. Nagai Y, Critchley HD, Featherstone E et al (2004) Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a “default mode” of brain function. Neuroimage 22:243–251

    Article  Google Scholar 

  49. Wager TD, Waugh CE, Lindquist M et al (2009) Brain mediators of cardiovascular responses to social threat: part I: reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity. Neuroimage 47:821–835

    Article  Google Scholar 

  50. Baumgärtner U, Buchholz HG, Bellosevich A et al (2006) High opiate receptor binding potential in the human lateral pain system. Neuroimage 30:692–699

    Article  Google Scholar 

  51. Iwamura Y (2000) Bilateral receptive field neurons and callosal connections in the somatosensory cortex. Philos Trans R Soc Lond B Biol Sci 355:267–273

    Article  Google Scholar 

  52. van Stralen HE, van Zandvoort MJE, Dijkerman HC (2011) The role of self-touch in somatosensory and body representation disorders after stroke. Philos Trans R Soc Lond B Biol Sci 366:3142–3152

    Article  Google Scholar 

  53. Heydrich L, Blanke O (2013) Distinct illusory own-body perceptions caused by damage to posterior insula and extrastriate cortex. Brain 136:790–803

    Article  Google Scholar 

  54. Hauck M, Lorenz J, Engel AK (2007) Attention to painful stimulation enhances gamma-band activity and synchronization in human sensorimotor cortex. J Neurosci 27:9270–9277

    Article  Google Scholar 

  55. Paulus MP, Stein MB (2006) An insular view of anxiety. Biol Psychiatry 60:383–387

    Article  Google Scholar 

  56. Stevens FL, Hurley RA, Taber KH (2011) Anterior cingulate cortex: unique role in cognition and emotion. J Neuropsychiatry Clin Neurosci 23:121–125

    Article  Google Scholar 

  57. Shackman AJ, Salomons TV, Slagter HA et al (2011) The integration of negative affect, pain and cognitive control in the cingulate cortex. Nat Rev Neurosci 12:154–167

    Article  Google Scholar 

  58. Naqvi N, Shiv B, Bechara A (2006) The role of emotion in decision making. Curr Dir Psychol 15:260–264

    Article  Google Scholar 

  59. van Stralen HE, van Zandvoort MJE, Dijkerman HC (2011) The role of self-touch in somatosensory and body representation disorders after stroke Phil Trans R Soc B 366:3142–3152

    Google Scholar 

  60. Kammers MP, de Vignemont F, Haggard P (2010) Cooling the thermal grill illusion through self-touch. Curr Biol 20:1819–1822

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Frontier Health Science, Division of Human Health Sciences, Graduate School of Tokyo Metropolitan University, 7-2-10, Higashi-Ogu, Arakawa-Ku, Tokyo, 116-8551, Japan

    Yoshiaki Kikuchi & Madoka Noriuchi

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  1. Yoshiaki Kikuchi
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  2. Madoka Noriuchi
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Correspondence to Yoshiaki Kikuchi .

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  1. System Design and Management Research Institute, Keio University, Minato-ku, Tokyo, Japan

    Shuichi Fukuda

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Kikuchi, Y., Noriuchi, M. (2019). Power of Self-Touch: Its Neural Mechanism as a Coping Strategy. In: Fukuda, S. (eds) Emotional Engineering, Vol.7. Springer, Cham. https://doi.org/10.1007/978-3-030-02209-9_3

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  • DOI: https://doi.org/10.1007/978-3-030-02209-9_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-02208-2

  • Online ISBN: 978-3-030-02209-9

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