Abstract
We present four entropy-based methods for colour segmentation within a lesion in a dermoscopy image for classification of the image as melanoma or benign. Four entropy segmentation methods are based on Tsallis, Havrda and Charvat, Renyi and Kapur entropy measures. Segmentation through Six Sigma threshold as preprocessor is also evaluated by this assessment approach. The proposed methods are inspired by two clinical observations about melanoma. First, colours within a lesion provide the most useful measures for melanoma detection; second, the disorder in colour variety and arrangement provides the best assessment of melanoma colours. These observations lead to the hypothesis that colour disorder is best measured by entropy. The five different models for colour splitting studied with SSIM measures taken from each region in the colour-split image for segmentation assessment. Based on the score helps to understand segmentation region assessment effectively.
Keywords
- Image analysis
- Melanoma
- Structural similarity measure
- Dermoscopy
- Image segmentation
- Information entropy
- Lesion segmentation
- Skin cancer
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References
Siegel RL, Miller KD, Jemal A (2017) Cancer statistics. CA Cancer J Clin 64(1):9–29
Weinstein DA, Konda S, Coldiron BM (2017) Use of skin biopsies among dermatologists. Dermatol Surg 43(11):1348–13657
Esteva A, Kuprel B, Novoa RA et al (2017) Dermatologist-level classification of skin cancer with deep neural networks. Nature 542(7639):115–118
Ferris LK, Harkes JA, Gilbert B et al (2015) Computer-aided classification of melanocytic lesions using dermoscopic images. J Am Acad Dermatol 73(5):769–76
Pehamberger H, Binder M, Steiner A et al (1993) In vivo epiluminescence microscopy: improvement of early diagnosis of melanoma. J Invest Dermatol 100:356S–362S
Soyer HP, Argenziano G, Chimenti S, Ruocco V (2001) Dermoscopy of pigmented skin lesions. Eur J Dermatol 11(3):270–277
Soyer HP, Argenziano G, Talamini R, Chimenti S (2001) Is dermoscopy useful for the diagnosis of melanoma? Arch Dermatol 137(10):1361–1363
Stolz W, Braun-Falco O, Bilek P, Landthaler M, Burgdorf WHC, Cognetta AB (eds) (2002) Color atlas of dermatoscopy. Wiley-Blackwell, Hoboken
Braun RP, Rabinovitz HS, Oliviero M, Kopf AW, Saurat JH (2002) Pattern analysis: a two-step procedure for the dermoscopic diagnosis of melanoma. Clin Dermatol 20(3):236–239
Boldrick JC, Layton CJ, Nguyen J, Swetter SM (2007) Evaluation of digital dermoscopy in a pigmented lesion clinic: clinician versus computer assessment of malignancy risk. J Am Acad Dermatol 56(3):417–421
Perrinaud A, Gaide O, French LE, Saurat JH, Marghoob AA, Braun RP (2007) Can automated dermoscopy image analysis instruments provide added benefit for the dermatologist? A study comparing the results of three systems. Br J Dermatol 157(5):926–933
Mishra NK, Celebi ME (2016) An overview of melanoma detection in dermoscopy images using image processing and machine learning. arXiv preprint arXiv:1601.07843
Rosendahl et al (2012) Dermatoscopy in routine practice: ‘Chaos and clues’. Aust Fam Physician 41(7):482
Friedman RJ et al (1985) Early detection of malignant melanoma: the role of physician examination and self-examination of the skin. CA Cancer J Clin 35(3):130–151
Rubegni P et al (2015) Computer-assisted melanoma diagnosis: a new integrated system. Melanoma Res 25(6):537–542
Andreassi L et al (1999) Digital dermoscopy analysis for the differentiation of atypical nevi and early melanoma: a new quantitative semiology. Arch Dermatol 135(12):1459–1465
Landau M et al (1999) Computerized system to enhance the clinical diagnosis of pigmented cutaneous malignancies. Int J Dermatol 38(6):443–446
Umbaugh SE et al (1989) Automatic color segmentation of images with application to detection of variegated coloring in skin tumors. Eng Med Biol Mag IEEE 8(4):43–50
Aitken JF et al (1996) Reliability of computer image analysis of pigmented skin lesions of Australian adolescents. Cancer 78(2):252–257
Ercal F et al (1994) Neural network diagnosis of malignant melanoma from color images. IEEE Trans Biomed Eng 41(9):837–845
Ganster H et al (2001) Automated melanoma recognition. IEEE Trans Med Imaging 20(3):233–239
Kaushik RHC et al. (2013) The median split algorithm for detection of critical melanoma color features. In: International conference on computer vision theory and applications (VISAPP), pp 492–495
Stanley RJ et al (2007) A relative color approach to color discrimination for malignant melanoma detection in dermoscopy images. Skin Res Technol 13(1):62–72
Almubarak HA et al (2017) Fuzzy color clustering for melanoma diagnosis in dermoscopy images. Information 8(3):89
Sabbaghi Mahmouei SA et al. (2015) An improved colour detection method in skin lesions using colour enhancement. In: Australian biomedical engineering conference (ABEC 2015)
Madooei A et al (2013) A colour palette for automatic detection of blue-white veil. In: Color and imaging conference, vol 2013, no 1, pp 200–205
Tiwari R, Sharma B (2016) A comparative study of Otsu and entropy based segmentation approaches for lesion extraction. In: Conference: 2016 international conference on inventive computation technologies (ICICT)
Sankaran S, Malarvel M, Sethumadhavan G, Sahal D (2017) Quantitation of malarial parasitemia in giemsa stained thin blood smears using six sigma threshold as preprocessor. Optik Int J Light Electr Opt 145:225–239. ISSN 0030-4026, http://dx.doi.org/10.1016/j.ijleo.2017.07.047
Comparison of Shannon, Renyi and Tsallis Entropy used in Decision Trees, Tomasz Maszczyk and Wlodzislaw Duch
Ja Havrda, František Charvát (1967) Quantification method of classification processes: concept of structural a-entropy. Kybernetika 03(1):30–35
Kapur JN, Sahoo PK, Wong AKC (1985) A new method for Gray-level picture thresholding using the entropy of the histogram. Comp Vis Graphics Image Process 29:273–285. https://doi.org/10.1016/0734-189X(85)90125-2
Rényi A (1961) On measures of entropy and information. In: Proceedings of the fourth Berkeley symposium on mathematical statistics and probability, Volume 1: contributions to the theory of statistics, pp 547–561. University of California Press, Berkeley, California. http://projecteuclid.org/euclid.bsmsp/1200512181
http://web.mit.edu/2.810/www/files/readings/ControlChartConstantsAndFormulae.pdf
Sankaran S, Sethumadhavan G (2013) Quantifications of asymmetries on the spectral bands of MALIGNANT melanoma using six sigma threshold as preprocessor. In: Third international conference on computational intelligence and information technology (CIIT 2013), Mumbai, pp 80–86. https://doi.org/10.1049/cp.2013.2575
Wang Z, Bovik AC, Sheikh HR, Simoncelli EP (2004) Image quality assessment: from error visibility to structural similarity. IEEE Trans Image Process 13(4):600–612. https://doi.org/10.1109/tip.2003.819861
Acknowledgements
This publication was made possible by SBIR Grants R43 CA153927-01 and CA101639-02A2 of the National Institutes of Health (NIH). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. Further, the authors would like to acknowledge the support rendered by the management of SASTRA Deemed to be University, Tirumalaisamudram, India.
This work is a by-product of generic image processing tool named “Bhadraloka” being developed (Dot Net platform) in SASTRA for the project titled “Development of techniques for processing radiographic images for automated detection of defects” with the funding assistance from Board of Research in Nuclear Science (BRNS), Department of Atomic Energy, Government of India (No. 2013/36/40-BRNS/2305).
Also, SS would like to thanks HCL Technologies Limited in supporting all through this research work.
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Sankaran, S., Hagerty, J.R., Malarvel, M., Sethumadhavan, G., Stoecker, W.V. (2019). A Comparative Assessment of Segmentations on Skin Lesion Through Various Entropy and Six Sigma Thresholds. In: Pandian, D., Fernando, X., Baig, Z., Shi, F. (eds) Proceedings of the International Conference on ISMAC in Computational Vision and Bio-Engineering 2018 (ISMAC-CVB). ISMAC 2018. Lecture Notes in Computational Vision and Biomechanics, vol 30. Springer, Cham. https://doi.org/10.1007/978-3-030-00665-5_19
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