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Prevention of Substance Use pp 233–246Cite as

The Importance of Mediation Analysis in Substance-Use Prevention

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Part of the book series: Advances in Prevention Science ((Adv. Prevention Science))

Abstract

This chapter describes the theoretical and practical importance of mediation analysis in substance-use prevention research. The most important reason for including mediators in a research study is to examine the mechanisms by which prevention programs influence substance-use outcomes. Understanding the mechanisms by which prevention programs achieve effects helps reduce the cost and increases effectiveness of prevention programs. This chapter first describes the theoretical foundations of the mediation model in prevention, and reasons for using mediation analysis in substance-use prevention. Next, we provide an overview of statistical mediation analysis for single and multiple mediator models. We summarize mediation analyses in substance-use prevention and discuss future directions for application of mediation analysis in substance-use research.

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Authors and Affiliations

  1. T. Denny Sanford School of Social and Family Dynamics, Arizona State University, Tempe, AZ, USA

    Holly P. O’Rourke

  2. Psychology Department, Arizona State University, Tempe, AZ, USA

    David P. MacKinnon

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  1. Holly P. O’Rourke
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  2. David P. MacKinnon
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Correspondence to Holly P. O’Rourke .

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Editors and Affiliations

  1. Applied Prevention Science International, Ontario, OH, USA

    Zili Sloboda

  2. AIR, Washington, DC, USA

    Hanno Petras

  3. University of Alabama, Tuscaloosa, AL, USA

    Elizabeth Robertson

  4. Division of Epidemiology and Prevention Research, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA

    Ralph Hingson

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O’Rourke, H.P., MacKinnon, D.P. (2019). The Importance of Mediation Analysis in Substance-Use Prevention. In: Sloboda, Z., Petras, H., Robertson, E., Hingson, R. (eds) Prevention of Substance Use. Advances in Prevention Science. Springer, Cham. https://doi.org/10.1007/978-3-030-00627-3_15

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