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HIV, HTLV and Cancer

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Progress in Anti-Cancer Chemotherapy

Part of the book series: Progress in Anti-Cancer Chemotherapy ((ANTI-CANCER,volume 4))

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Abstract

First described by Rous in 1911 as filterable agents capable of inducing sarcomas in chickens, retroviruses (initially called RNA tumor viruses) are among the earliest known viruses. In the 1950s and -60s these agents were found to cause a variety of mammalian cancers and leukemias and were shown to be RNA viruses. Human retroviruses were first described beginning in 1979, and their link etiologically to human leukemia (HTLV) and subsequently to Kaposi’s Sarcoma and Non-Hodgkins Lymphoma (HIV) represents some of the most important advances in biologic research in decades. In this chapter, we will summarize the available knowledge regarding the oncologic potential of the HTLV family (onco-retroviruses), and the HIV family (lente retroviruses).

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Authors
  1. F. R. Cleghorn
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  2. R. C. Gallo
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Editors and Affiliations

  1. Pitié-Salpétrière Hospital SOMPS, 47, bd de l’Hôpital, 75651, Paris Cedex 13, France

    David Khayat

  2. MD Anderson Cancer Center, Department of Breast Medical Oncology, University of Texas, 1515 Holcombe Boulevard, 77030, Houston, Texas, USA

    Gabriel N. Hortobagyi

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Cleghorn, F.R., Gallo, R.C. (2000). HIV, HTLV and Cancer. In: Khayat, D., Hortobagyi, G.N. (eds) Progress in Anti-Cancer Chemotherapy. Progress in Anti-Cancer Chemotherapy, vol 4. Springer, Paris. https://doi.org/10.1007/978-2-8178-0920-5_4

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  • DOI: https://doi.org/10.1007/978-2-8178-0920-5_4

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