Abstract
The classical treatment of T3 Bladder Cancer is surgery. The place of irradiation remains limited, for example in the frame of associated radio-surgery protocol. The incidence of pathological down-staging following 40–50 Gy preoperative irradiation has been noted in more than 60 % of patients, and the incidence of histologically positive lymph nodes is half of the expected incidence (20 %). But only 30 to 40 % of the patients, with clinical T3 bladder cancer have no tumor in cystectomy specimen after pre-operative irradiation. Furthermore, in the NSABP trial, the survival of patients who were down-staged to pT0 enjoyed a significant survival advantage over patients whose tumors were not down-staged [1].
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© 1991 Springer-Verlag France
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Housset, M. et al. (1991). Preliminary results of a protocol of pre-operative radiation therapy with concomitant chemotherapy for invasive bladder cancer. In: Banzet, P., Holland, J.F., Khayat, D., Weil, M. (eds) Proceedings of the 3rd International Congress on Neo-Adjuvant Chemotherapy. Springer, Paris. https://doi.org/10.1007/978-2-8178-0782-9_27
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DOI: https://doi.org/10.1007/978-2-8178-0782-9_27
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