Etiological Diagnosis of Central Precocious Puberty

  • Regis CoutantEmail author


Central precocious puberty is defined by the premature activation of pulsatile GnRH secretion from the hypothalamus. The cause may be a hypothalamic lesion (a tumor or other alteration) but is most often of unknown origin (idiopathic central precocious puberty). In the latter case, the triggering factor may be genetic (genomic mutations), epigenetic, or environmental (endocrine disruptors), but usually cannot be identified. The main etiologies are listed in Table 6.1 [1, 2] and will be discussed below.


Congenital Adrenal Hyperplasia Arachnoid Cyst Endocrine Disruptor Precocious Puberty Excessive Weight Gain 
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© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Endocrinologie pédiatriqueCHU AngersAngersFrance

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